“A STUDY ON PRESCRIBING PATTERN OF ANTIMICROBIAL AGENTS IN PATIENTS SUFFERING FROM PELVIC INFLAMMATORY DISEASE IN A TERTIARY CARE TEACHING HOSPITAL”
Anju Paulose*, Bharathi D.R.1, B. Shankar Reddy1, Anju Arpana2, Anto John1, Anu Rajan1, Rahul Jose1, Y Satyakrishna1
1Department of Pharmacy Practice, SJMCP, Chitradurga, Karnataka, India.
2Department of OBG, BMCH & RC, Chitradurga, Karnataka, India.
Pelvic inflammatory disease (PID) constitute the Upper reproductive tract infection in women and a major health concern leading to profound gynaecological morbidity among women in reproductive age group with impact on individual women, their families and communities. These infections entail a heavy toll on women, if untreated they can cause long-term complications, such as tubal infertility, ectopic pregnancy, chronic pelvic pain and abortions. Objectives: To analyze and evaluate the rationality of prescribing pattern of AMAs in PID and to monitor the ADRs & drug interactions, if any, with AMAs & concomitant drugs. Materials and Methods: A six months prospective observational study was carried out at OBG In-Patient department of Basaveshwara Medical College Hospital & Research Centre, Chitradurga. Results: A total of 85 patients were enrolled in the study aged above 18 years from the OBG In-Patient department. Coming to the prescription pattern of antibiotics Nitroimidazoles & Cephalosporin’s were majority of 36.36% & latter with 29.54. Coming to the concomitant drugs, NSAIDs & antacids were major in proportions (7.24% & 44.15%). Coming to the combination of antibiotics mostly prescribed drugs were Nitroimidazoles + Cephalosporins (37.34%) & Nitroimidazoles + Fluoroquinolones(13.29%). Conclusion: This study concludes that Nitroimidazoles & Cephalosporins were the first line choice of antibiotics in PID either alone or combination of same. NSAIDs with the combination of Aceclofenac/Diclofenac with Camylofin were mostly preferred for relieving pain & antacids were co-prescribed with NSAIDs to avoid NSAID induced gastric irritation.