The aim of this work is to formulate and test a compact herbal powder from herbal ingredients for cosmetic purposes and anti acne use. Ingredients like Gum Arabic, Glycerol, Talc, Kaolin, Titanium dioxide, Zinc stearate, Garlic and Nutmeg are purchased from local store and then passed through sieve, preparation of binder, mixed thoroughly prepared and evaluated for its organoleptic, physicochemical characters and antimicrobial evaluation. The combined-form dried powder had a passable flow property appropriate for a compact face powder. Herbal compact powders are used as a base for your entire makeup routine and anti-acne activity as it contains garlic extract which is having prominent activity against Pseudomonas aureginosa and Escherichia coli. Thus in this present work, we found good properties of herbal compact powder and find the useful benefits.

This review intends to assess the possibilities of novel vesicular drug delivery systems for targeting. Novel drug delivery seeks to either sustain drug action at a predetermined rate or maintain an adequately constant, adequate drug level in the body with associated minimization of unwanted side effects. An NDDS delivers drugs at a fixed rate decided as per the body’s requirement, pharmacological aspects, drug profile, and physiological conditions. In present conditions, not a single novel drug delivery system acts ideally with fewer side effects. The vesicular system's aim in drug delivery has changed the definition of diagnosis and treatment in different biomedical field aspects “A vesicular drug delivery system is the system in which the protection of active ingredients in a vesicular structure which bridges the gap between ideal and availability of novel drug delivery system.” Several vesicular drug delivery systems like Liposomes, Niosomes, Proniosomes, Transferosomes, Pharmacosomes, Colloidosomes, Herbosomes, Sphingosomes, Aquasomes, Ufasomes, and Electrosomes have been developed. This review includes a discussion about various lipoidal and non-lipoidal vesicular drug targeting.  

The objective of this study is to develop a novel, rapid and  sensitive UV spectrophotometeric technique for the determination of Fostemsavir in bulk and pharmaceutical dosage form . The solvent used was phosphate buffer pH 6.8 and the maximum absorbance  was recorded at 278 nm. Analytical calibration curves were linear within a concentration range of 7.5 to 45?g/ml and coefficient of correlation 0.999. The percentage RSD was found to be less than 2. The result of analysis has been validated statistically. This method was validated in accordance with ICH requirements which included the  parameters like linearity, accuracy ,precision, sensitivity, specificity and robustness. Hence the proposed method can be used for the reliable quantification of Fostemsavir in bulk and tablet formulation. The present outcome of research summarizes that the method is suitable for routine analysis for the determination of Fostemsavir.