A COMPREHENSIVE STUDY ON METABOLIC SYNDROME (NCEPATP III) AND FRAMINGHAM RISK SCORE IMPLIED CVD RISK ASSESSMENT AND MANAGEMENT OF CARDIOMETABOLIC RISK FACTORS
Dr. Dharitri G. Joshi¹*, Riya Johns1, Rinju Sara Rajan1, Nagpavan S R1, KanchalP.Sudeesh1
Doctor of Pharmacy, Department of Pharmacy Practice, Bapuji Pharmacy College, Davangere, Karnataka (Dist.), Pin : 577004.
Objectives: The objectives of the study were to screen the patients for MetSusing NCEPATP-III criteria, to predict the prevalence of CVD risk using FRS and to find out various risk factors associated with CVD. Methodology: Across sectional study was conducted for a period of 6 months. The ethical clearance was obtained from the institutional ethical committee of Bapuji Pharmacy College, Davangere. The estimated sample size was 278. Patients were screened for MetS andCVD risk assessment was done using non – laboratory - based FRS. Categorical data were analyzed using Chi-square test. Quantitative variables were analyzed using unpaired t-test and one way ANOVA. Results: Out of 278 participants, 71.9% had MetSand 28.05% did not have MetS. The participants with three MetScomponents had the highest prevalence of high CVD risk. Using multiple logistic regression, the significant predictors of CVD risk by FRS were male gender (OR=1.00), age 51–70 years (OR=1.13), BMI between 25–29.9 kg/m2 (OR=1.083 for high and OR=1.086 for moderate CVD risk), SBP between140–150 mm Hg (OR=1.028), and FBS 126mg/dl (OR=1.00). Conclusion: Participants with three MetS risk factors had the highest prevalence of high CVD risk Therefore, awareness about the risk factors associated with MetS and the necessity for managing proper dietary pattern and its associated cardiovascular risk.