Computer is mandatory in this advanced era and pharmacy and related subjects are not exception to it. This review mainly focuses on the various applications, softwares and use of computers in pharmacy. Computer science and technology is deeply utilized in pharmacy field everywhere like in pharmacy colleges, pharmaceutical industries, research centers, hospital pharmacy and many more. Computer significantly reduces the time, expenditure, and manpower required for any kind of work. Development of various softwares makes it trouble-free to handle huge data. In short, computers are playing critical role in pharmacy field, without computers pharmacy research will be long-lasting and expensive. This review mainly focuses on the various applications, softwares and uses of computers in pharmacy. Computer science and technology is deeply used in the pharmacy sector like pharmacy colleges, pharmaceutical industries, research centers, hospital pharmacy and many more.

Candesartan cilexetil (CAN), a prominent angiotensin II receptor blocker (ARB), has gained significant attention in cardiovascular medicine. This comprehensive review article delves into various facets of CAN, ranging from its pharmacology and pharmacodynamics to drug interactions, contraindications, and adverse reactions. The pharmacological profile of this compound is explored, elucidating its mechanism of action and its role in modulating the renin-angiotensin-aldosterone system. A detailed description of CAN, its formulation, tablet names, brand names, and compositions, is presented in a tabular format for quick reference. A crucial aspect of this review is the discussion of drug interactions, highlighting potential combinations that require caution and vigilant monitoring. Robust analytical techniques are vital for quality control, bioavailability assessment, and bioequivalence studies. Moreover, this article goes beyond clinical aspects by encompassing analytical methods employed in the quantification of CAN. The incorporation of analytical methods provides a comprehensive overview of the scientific methodologies used to measure CAN concentrations in biological samples. 

Snake bites cause major death and morbidity all across the world, including India. Despite the fact that there are numerous snake species, only a handful of them are potentially harmful to people. Snake antivenom is the only treatment choice for snake bite therapy, although it has several limitations in clinical practise, such as species specificity, difficulties in availability, price, and appropriate storage conditions. The medicinal plants, which are locally available and frequently employed by traditional healers, require special consideration in this regard. A large range of botanicals and active principles have been studied for their pharmacological qualities in the treatment of snake bites. However, other unknown plants that are reported to have a significant part in this issue must be investigated further. Antiserum, on the other hand, does not give adequate protection against venom-induced haemorrhage, necrosis, and nephrotoxicity, and it frequently causes hypersensitivity responses. India has a long history of medicinal plant use. Many Indian medicinal herbs, particularly in rural regions, are described in literature as being used to heal snakebite victims. Only a few species, however, have been professionally researched, and even fewer have had their active components extracted and structurally and functionally defined. 

Tinospora cordifolia is one of the important medicinal plants, commonly referred as a rejuvenating herb. It has significant antimicrobial properties and that features found in stem, leaves, extract for microorganisms. T.cordifolia silver nanoparticles have significant antimicrobial activity, the alkaloids such as Berberine; present in the T.cordifolia herbal plant also gives the significant antimicrobial effects, which makes them a powerful source of antimicrobial agent. In the recent research findings, there are few topical gel formulations of AgNPs by green synthesis method and until now T.cordifolia silver nanoparticles incorporated in gel have not been formulated. Thus, the present research study aims to formulate and evaluate the Topical Nano silver gel of T.cordifolia (Guduchi) to minimize potential microbial infections. The green synthesis of silver nanoparticles was conducted by using T. cordifolia leaves and stem extract. The Preformulation studies were performed for the determination of presence of phytoconstituents such as alkaloids, flavonoids, glycosides etc. The characterization of T. cordifolia AgNPs was performed by UV spectroscopy studies, Percentage Entrapment efficiency, Fourier Transform Infrared Spectroscopy (FTIR). Particle size analysis; Zeta potential, SEM studies .The AgNPs of T. cordifolia and the extract was evaluated for Antimicrobial activity against Staphylococcus aureus& E. coli. The synthesized AgNPs of T. cordifolia was incorporated to gel base. That gel formulation evaluated for the physicochemical parameters such as pH, viscosity, spreadability, extrudability and also the antimicrobial activity against E. coli. The antimicrobial study of prepared Nano silver gel of T. cordifolia exhibited effective antimicrobial properties against E. coli. Hence; this study concluded that the formulated Nano silver gel of T. cordifolia can be used as an effective formulation for the treatment of antimicrobial infections. 

Human Immunodeficiency Virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) continue to pose a significant global health burden, demanding novel strategies to combat this devastating pandemic. Gene therapy, a cutting-edge therapeutic approach, has emerged as a promising avenue for revolutionizing the treatment landscape by offering a potential cure for HIV and AIDS. This review article provides a comprehensive analysis of the advancements made in gene therapy research, highlighting the diverse modalities employed and their efficacy in combating HIV infection. From traditional gene editing tools, such as zinc finger nucleases and transcription activator-like effector nucleases, to the breakthrough CRISPR-Cas9 system, this appraisal delves into the gene editing technologies employed to target and manipulate the HIV genome. Additionally, the versatile approaches utilized in gene therapy, including gene augmentation, gene silencing, and immune cell engineering, are explored in the context of HIV and AIDS treatment. Furthermore, we addressed ethical considerations associated with this revolutionary approach. By providing a comprehensive overview of the current state of gene therapy for HIV and AIDS, this review aims to inspire further research and foster the development of curative strategies, paving the way towards an eventual cure for this global health crisis.

The Satyanashi plant (Botanical name: Satyanashi sp.) has a rich history of Ethnomedicinal, therapeutic, and traditional usage in various indigenous systems of medicine across diverse cultures. This review aims to comprehensively explore and document the wide spectrum of applications attributed to the Satyanashi plant in traditional healing practices. Ethnomedicinal knowledge, passed down through generations, has contributed to the understanding of the plant's therapeutic potential. Traditional healers have harnessed its diverse parts, including leaves, stems, roots, and flowers, for treating a variety of ailments. The plant's efficacy in addressing conditions such as gastrointestinal disorders, respiratory ailments, skin conditions, and reproductive health issues has garnered attention. Furthermore, the review highlights the phytochemical composition of the Satyanashi plant, revealing a plethora of bioactive compounds such as alkaloids, Flavonoids, Terpenoids, and Phenolics compounds. These constituents have been attributed to the plant's pharmacological activities, which include anti-inflammatory, antioxidant, antimicrobial, and analgesic properties. Such findings not only validate the traditional uses but also pave the way for potential modern pharmaceutical applications. The therapeutic potential of Satyanashi extends beyond its physiological effects, encompassing psychological and spiritual dimensions. Traditional rituals and ceremonies involving the plant demonstrate its cultural significance in promoting holistic well-being. The plant's role in traditional belief systems and cultural practices underscores its deep-rooted connection with local communities. However, despite its historical and potential value, the Satyanashi plant faces challenges such as habitat loss, overharvesting, and insufficient scientific validation. Conservation efforts, coupled with rigorous scientific research, are imperative to ensure the sustainable use and preservation of this valuable botanical resource. In conclusion, the Satyanashi plant exemplifies the intricate interplay between traditional knowledge, therapeutic efficacy, and cultural significance. By amalgamating insights from indigenous practices with contemporary scientific advancements, this review sheds light on the multifaceted nature of the plant. This endeavor underscores the importance of preserving and respecting traditional wisdom while harnessing it for the betterment of human health and well-being.