IAJPR

Indo American Journal of Pharmaceutical Research

ISSN NO.: 2231-6876
SEPTEMBER 2022
1

A CRITICAL STUDY OF SPECIFIC INDICATION OF PIPPALI KALKA AND SARIVA KALKA WITH KSHEERA IN PRAVAHIKA WITH SPECIAL REFERENCE TO RATNAPRABHA COMMENTARY OF NISHCHALKARA ON CHAKRADATTA SAMHITA.

Vd. Aditi R. Deshpande

MD (Scholar), CARC, Akurdi.

Pravahika is quite challenging to treat. It needs removal of mala but decrease in frequency of malavegas. Both actions are opposite in nature. So, drugs which can remove the mala out of the body without increasing the frequency of malavegas are needed. Chakradatta has given two simple formulations having two drugs opposite in nature. Pippali and Sariva are quite opposite in action and characters. In one of the manuscripts of Ratnaprabha, Maricha kalka with ksheera is given in chirakalanubandhiPravahika and in another manuscript, Maricha is replaced by Sariva for the same. P. V. Sharma sir has taken Sariva in the commentary published by Swami Jayaramdas Trust, 1993. So, Sariva is taken here for study. As the drugs having different characters are advised by the author, indication is more specified in this study with help of Rasa-dosha sambandha and Rasapanchaka of dravyas. So, the study helps to differentiate between the indication of two drugs to be used after proper diagnosis. 


 


2

PREPARATIVE ISOLATION AND CHARACTERIZATION OF POLYPHENOLS FROM ALPINIAGALANGALINN., GARCINIA INDICACHOISY AND GLYCYRRHIZAGLABRALINN., AND THEIR ROLE AS ANTI-OBESITY THERAPEUTICS RESEARCH PAPER

Miss. Sadhna Singh, Dr. Arvind Negi

Department of Pharmacognosy, GRD Institutes of Management and Technology. Rajpur Road Dehradun, Uttrakhand.

Alpinia galanga plant which is associated with family Zingiberaceae is mainly scattered in tropical areas and widely known for ethno medicine. Against fungi and bacteria rhizome extract have a maximum inhibitory effect. Alpinia galanga plant is used in medicine and in food preparation. Rhizome extract of Alpinia galanga have high phenolic and flavonoid contents when compared to leaf extract. Because of elevated phenolic and flavonoid content in rhizome extract of Alpinia galanga there is noticeable antimicrobial as well as radical scavenging potential. It is a well-known official drug thought out the country as integrated contribution of nature. It is commonly used for the management of eczema, coryza, bronchitis, otitis interna, gastritis, ulcers, morbilli and cholera, pityriasis versicolor, to clear the mouth, emaciation. The different parts of the plant have various effects like antifungal, antiprotozoal, antiplatelet, antiviral, antidiabetic, immunomodulatory, antibacterial, anti-oxidant effects, hypolipidemic and many others. The essential oil of A. galanga identified 1, 8-cineol as a bioactive agent having antifeeding activity. An aqueous acetone extract of fruit of Alpinia galanga shows inhibitory effect on melanogenesis (formation of melanin). By using different methods, active constituent namely, 1'- acetochavicol acetate in hexane extract of Alpinia galanga rhizome was investigated for their corrosion inhibition properties. The current review add significant information about its, pharmacological activities, medicinal properties and phytochemical investigations as a traditional drug to cure for a number of diseases. Every fraction of the plant has valuable properties that can deliver humanity. The complete plant will be broadly investigated for further future prospective