PHYTOCHEMICAL SCREENING AND EVALUATION OF IN VITRO HAEMOLYTIC, THROMBOLYTIC AND ANTIINFLAMMATORY ACTIVITIES OF AERVA LANATA (L.)
The present study was aimed to screen the phytochemicals and to determine the in vitro hemolytic, thrombolytic and anti-inflammatory activities of aqueous extracts of leaf, flower and root of Aerva lanata. The in vitro haemolytic activity of root, flower and leaf of A. lanata was determined against human erythrocytes. Thrombolytic activity of root, flower and leaf of A. lanata was evaluated against human blood clot (thrombosis). The anti-inflammatory activity of root, flower and leaf of A. lanata was studied by membrane stabilization method. The phytochemical analysis of aqueous extracts of A. lanata showed that the presence of bioactive secondary metabolites. The aqueous extracts of root possess minimum haemolytic activity against RBC membrane. So, it can be considered as safe for the human erythrocytes. The maximum level of lyses of clot by root extract of A. lanata was observed, which may be due to the presence of tannins, alkaloids and saponins. The highest protection / stabilization of Human Red Blood Cell (HRBC) membrane by the flower extract of A. lanata were observed. The results of this study confirmed that the medicinal plant A. lanata possess bioactive compounds and in vitro haemolytic, thrombolytic and anti-inflammatory properties. So, we concluded that this study may be helpful in future for the identification of new pharmaceutical drugs from leaf, flower and root of Aerva lanata to treat inflammatory disease, myocardial infarction and other heart diseases.