Abstract
Chitosan has been extensively researched for has important features such as: biocompatibility, biodegradability and low toxicity. These properties make it suitable biopolymer for use in the biomedical field, including artificial skin, tissue regeneration and controlled drug release system. The aim of this study was to prepare and characterize membranes based on chitosan with the glycerol and gentamicin in different proportions in order to improve the properties of the material. The results of FTIR, TG, DSC and X-rays indicate that the chitosan films containing glycerol and gentamicin are more stable when compared to the pure membranes. The results of SEM, swellings and the mechanical properties showed that the membranes have improved elasticity, making it more pliable, but its tensile strength decreases due to the presence of glycerol. Therefore, studies have shown that membranes prepared with chitosan, glycerol and gentamicin can be used in drug delivery systems and bandages on skin regeneration.
