Multiple Hereditary Exostoses (MHE) is a rare
autosomal dominant skeletal disorder characterized by multiple osteochondroma,
typically affecting long bones. This case report describes a 17-year-old female
with multiple swellings over the bilateral forearms and thighs since birth,
presenting with progressive pain in the left distal thigh. A positive family
history, clinical evaluation, and radiological findings confirmed the diagnosis
of MHE. Laboratory investigations revealed mild iron-deficiency anemia but no
other systemic abnormalities. HRCT incidentally detected a large osteochondroma
compressing the aortic arch. After comprehensive multispecialty assessments to
ensure surgical safety, the painful distal femoral osteochondroma was
surgically excised. Postoperative care included antibiotics, nutritional
supplementation, wound management, and physiotherapy, leading to a successful
recovery. This case highlights the variable presentation of MHE and underscores
the importance of early diagnosis, genetic evaluation, and surgical
intervention for symptomatic lesions to prevent complications and improve
patient outcomes
