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APRIL 2020

SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF ISONIAZID AND PYRIDOXINE

Anitha K*1, T. M. Kalyankar2, U. A. Khedkar2, R. B. Gholve2
1Department of Chemistry, Sri Krishnadevaraya University, Ananthapuram - 515003, Andhra Pradesh, India.

2School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded - 431606, Maharashtra, India.

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SIMULTANEOUS DETERMINATION OF METFORMIN AND GLIBENCLAMIDE IN PHARMACEUTICAL PREPARATION BY RP-HPLC

Anitha K¹, T. M. Kalyankar², V. B. Ingale² and Ashok P Gingine³

¹Department of Chemistry, Sri Krishnadevaraya University, Ananthapuram-515003, Andhra Pradesh, India.

²School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded (431 606), MS India.

³School of Educational Sciences, Swami Ramanand Teerth Marathwada University, Nanded (431 606), MS India.

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A VALIDATED RP- HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF ARTESUNATE, SULFADOXINE AND PYRIMETHAMINE IN BULK AND TABLETS FORMULATION

Anitha K¹, T. M. Kalyankar², Khan Jawad S. A.² and Ashok P Gingine³
¹Department of Chemistry, Sri Krishnadevaraya University, Ananthapuram-515003, Andhra Pradesh, India.
²School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded (431 606), MS India.
³School of Educational Sciences, Swami Ramanand Teerth Marathwada University, Nanded (431 606), MS India.

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A STUDY OF PATTERN OF REFERRALS IN LIAISON PSYCHIATRY

Dr Sally John^1*,Dr.Amrita Singam², Dr Sonia Mary Thomas³
¹Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi ,Wardha, Maharashtra Pin 442 001.
²Indira Gandhi Govt. Medical College, Department.of Pharmacology, Nagpur.
³Santhula Trust Hospital, Vadakkara, Oliyapuram P.O Kuthattukulam, Ernakulam Dt, Kerala.

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Liaison psychiatry specializes in bridging psychiatric services to other specialities. It has been actively intervening in the reduction of the communication gap between the various specialities in many health care setups. Thereby it provides them the ability to acquire adequate understanding about the intricacies involved in treating patients with physical and psychiatric co-morbidities. Efficient communication between different levels of care has a great impact on quality of health care. Objectives: To assess the source of referral, reason for referral, the psychiatric diagnosis of the patients referred and the Psychiatric treatment initiated by the referring team and the knowledge of the illness. Materials and method: The study was a cross sectional study conducted on the out patients and inpatients referred to the psychiatric department in a tertiary care hospital in central India. It was completed in the time period of 3 months from June 1st 2014 to August 15th 2014 with a sample size of 150 patients. All the referred patients were evaluated by a consultant psychiatrist and diagnosis was made according to the diagnostic guidelines of ICD-10 (International Classification of Diseases -10th Edition). Results: Out of the total number of patients who were referred 79(52.6%) patients were males and 71(47.3%) were females. The mean age of the study population was 36.01 years. A majority of the patients belonged to the age group of 21-30 years. A majority of the referrals were made from the department of medicine (n=76, 50.6%).The various reasons for psychiatric referral were analyzed and it was found that the most common reason was the presence abnormal behaviour (n=37, 24.6%). The most common psychiatric diagnosis made was substance use disorders (n=51, 34%) Conclusion: The observations of our study clearly show that there is significant gap existing in consultation liaison psychiatry as reflected in the profile and patterns referrals assessed. Early diagnosis and management of psychiatric disorders in patients presenting to the other departments with various physical illnesses definitely hasten recovery, reduce morbidity and improve quality of life. The way ahead is too long in this field and the need for improving the liaison is crucial in reducing the burden of morbidity and improving the quality of life of the patient and their carers.

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Liaison psychiatry specializes in bridging psychiatric services to other specialities. It has been actively intervening in the reduction of the communication gap between the various specialities in many health care setups. Thereby it provides them the ability to acquire adequate understanding about the intricacies involved in treating patients with physical and psychiatric co-morbidities. Efficient communication between different levels of care has a great impact on quality of health care. Objectives: To assess the source of referral, reason for referral, the psychiatric diagnosis of the patients referred and the Psychiatric treatment initiated by the referring team and the knowledge of the illness. Materials and method: The study was a cross sectional study conducted on the out patients and inpatients referred to the psychiatric department in a tertiary care hospital in central India. It was completed in the time period of 3 months from June 1st 2014 to August 15th 2014 with a sample size of 150 patients. All the referred patients were evaluated by a consultant psychiatrist and diagnosis was made according to the diagnostic guidelines of ICD-10 (International Classification of Diseases -10th Edition). Results: Out of the total number of patients who were referred 79(52.6%) patients were males and 71(47.3%) were females. The mean age of the study population was 36.01 years. A majority of the patients belonged to the age group of 21-30 years. A majority of the referrals were made from the department of medicine (n=76, 50.6%).The various reasons for psychiatric referral were analyzed and it was found that the most common reason was the presence abnormal behaviour (n=37, 24.6%). The most common psychiatric diagnosis made was substance use disorders (n=51, 34%) Conclusion: The observations of our study clearly show that there is significant gap existing in consultation liaison psychiatry as reflected in the profile and patterns referrals assessed. Early diagnosis and management of psychiatric disorders in patients presenting to the other departments with various physical illnesses definitely hasten recovery, reduce morbidity and improve quality of life. The way ahead is too long in this field and the need for improving the liaison is crucial in reducing the burden of morbidity and improving the quality of life of the patient and their carers.

FORMULATION DEVELOPMENT AND EVALUATION OF ORODISPERSIBLE TABLETS OF VALSARTAN USING SPRAY DRIED DILUENTS

MahaleNitin B^*1, Battase A.P².
¹Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Rajasthan, India.
²GovindraoNikam College of Pharmacy, Sawarde, Tal ChiplunDistRatnagiri, (M.S), India.

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FORMULATION DEVELOPMENT AND EVALUATION OF NOVEL ORODISPERSIBLE TABLETS OF OLMESARTAN

Mahale Nitin B^*1, Battase A.P².
¹Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Rajasthan, India.
²GovindraoNikam College of Pharmacy, Sawarde, Tal ChiplunDistRatnagiri, (M.S), India.

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A REVIEW: PULSATILE DRUG DELIVERY SYSTEM

Peruboina Neelima*, Maddula Venkata Ramana, Rama Rao Nadendla
Department of Pharmaceutics, Chalapathi Institute of Pharmaceutical Sciences, Lam, Guntur-522034, A.P, India.

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HAIR CARE PROMISING HERBS: A REVIEW

K. Rashid*, V. Baskar Ananda Raj, P. S Shiji Kumar, K.M Nishad
Jamia Salafiya Pharmacy College, Pulikkal, Malappuram-673637 Kerala.

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MICROSPHERES: REVIEW

Kaveri Wagh*, Krutanjali Rajesh Nikumbh, Nidhi Ashish Parikh, Dheeraj Raghunath Chavan, Shailesh Ram Kokani, Ranjana Prakash Guroda, Ansari Sadiya Bano Habeeburrahman
Royal College of Pharmaceutical Education & Research SayneKhurd, Malegaon, Dist. Nashik [423203] Maharashtra, India.

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A SHORT REVIEW ON CANAVAN DISEASE

G.V.K.S.Abhinav
Koringa College of Pharmacy, Kakinada, Andhra Pradesh, India.

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COMPARITIVE PHYTOCHEMICAL SCREENING, HEAVY METAL ANALYSIS BY AAS AND IN VITRO ANTI INFLAMMATORY ACTIVITY OF MARKETED AND IN HOUSE FORMULATIONS OF UDARKALP CHURNA

P. Sai Harshita*, R. Kanchan Sonali, M. Rajeshwari, P. Aarthi, P. Girija Sravani, Leemol Shaju, V. Jyothi
Sarojini Naidu Vanita Pharmacy Maha Vidyalaya Tarnaka- 500017.

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ORGAN TRANSPLANT A SYSTEM WITHIN ITSELF

Neha Naaz*, Aaminah Najmus Sahar, Khadija Akhtar Omer, Humaira Minhaj, Sufia Iram Irshad.
Department of Pharmacy Practice, Deccan School of Pharmacy(DSOP),OU,Hyderabad500001,Telangana,India.

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PREVALENCE AND DETERMINANTS OF INFLUENZA VACCINE ADMINISTRATION AMONG HEALTH CARE WORKERS AT PRIMARY HEALTHCARE CENTERS OF THE MINISTRY OF HEALTH IN JEDDAH 2019

Layan Arafah¹, Shaimaa Hawsawi¹, Amal Alfaifi¹, Widad Berdisi¹, Naeema Akbar²
¹Family Medicine Program, Public Health Department, Jeddah, Saudi Arabia.
²Clinical Preventive Medicine, Public Health Department, Jeddah, Saudi Arabia.

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MICROWAVE ASSISTED SYNTHESIS OF 1, 8-DIOXOOCTAHYDROXANTHENES USING PHOSPHONITRILIC CHLORIDE AS CATALYST

Sanjeev M. Reddy¹, Jitendra S. Pulle²
¹G.M.V. Kotgyal, Dist. Nanded (M.S.) India.
²S.G.B. College, Purna (Jn.), Dist. Parbhani (M.S.), India.

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PRESCRIPTION PATTERN IN MANAGEMENT OF VITILIGO IN A TERTIARY CARE CENTRE; A PROSPECTIVE OBSERVATIONAL STUDY

Dr. Amrita Singam, Dr. Mrunalini Chokhandre, Dr. Parul Gaikwad

Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur.

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COMPARITIVE PHYTOCHEMICAL SCREENING, HEAVY METAL ANALYSIS BY AAS AND IN VITRO ANTI INFLAMMATORY ACTIVITY OF MARKETED AND IN HOUSE FORMULATIONS OF UDARKALP CHURNA

P. Sai Harshita*, R. Kanchan Sonali, M. Rajeshwari, P. Aarthi, P. Girija Sravani, Leemol Shaju, V. Jyothi
Sarojini Naidu Vanita Pharmacy Maha Vidyalaya Tarnaka- 500017.

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INTELLECTUAL PROPRIETY RIGHTS: REVIEW

Pravin Tryambak Netkar*, Mohammed Awais Iqbal, Momin Nashra Sohail, Farooqui Nilofar Mohammad Jameel
Royal College of Pharmaceutical Education & Research, SayneKhurd, Malegaon, Dist. Nashik [423203] Maharashtra, India.

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PREVALENCE AND DETERMINANTS OF INFLUENZA VACCINE ADMINISTRATION AMONG HEALTH CARE WORKERS AT PRIMARY HEALTHCARE CENTERS OF THE MINISTRY OF HEALTH IN JEDDAH 2019

Layan Arafah¹, Shaimaa Hawsawi¹, Amal Alfaifi¹, Widad Berdisi¹, Naeema Akbar²
¹Family Medicine Program, Public Health Department, Jeddah, Saudi Arabia.
²Clinical Preventive Medicine, Public Health Department, Jeddah, Saudi Arabia

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Background: Influenza is a substantial threat to healthcare settings, and the annual influenza vaccine (IV) is an effective preventive measure against influenza. However, the vaccination rate among health care workers (HCWs) remains low. Objective: This study aimed at assessing vaccine coverage among HCWs at the primary health care centers of the Saudi Ministry of Health (MOH), and determine factors affecting compliance to vaccination. Methods: We conducted a cross-sectional study, and by applying a multistage clustering sample method, we randomly selected 83 male and 202 female HCWs. We used a self-administered questionnaire to collect information about IV uptake and its determinants. We performed the chi-square test to define associated factors and used binomial logistic regression analysis to determine the unconfounded predictors of IV. Results: The rate of IV among HCWs ranged from 53.3% during 2016 to 51.7% during the 2018 season. Compliances to successive vaccination over the past three years were only 30.2%; however, 66.2% of HCWs intended to receive the vaccine during the upcoming season. The main reasons for IV uptake included self-protection against influenza (60.7%) and caring about client's patients (44.8%). Single female nurses were more likely to be immunized against IV than other HCWs p<0.05. Both reading the official MOH IV guidelines and feeling of having sufficient knowledge about IV were unconfounded predictors for the vaccine. Conclusion: The overall immunization coverage was suboptimal, and the fact that reading the official MOH IV guidelines had a strong statistical association with a positive attitude towards vaccination emphasizes the role of governmental authorities in enhancing vaccine among the HCWsBackground: Influenza is a substantial threat to healthcare settings, and the annual influenza vaccine (IV) is an effective preventive measure against influenza. However, the vaccination rate among health care workers (HCWs) remains low. Objective: This study aimed at assessing vaccine coverage among HCWs at the primary health care centers of the Saudi Ministry of Health (MOH), and determine factors affecting compliance to vaccination. Methods: We conducted a cross-sectional study, and by applying a multistage clustering sample method, we randomly selected 83 male and 202 female HCWs. We used a self-administered questionnaire to collect information about IV uptake and its determinants. We performed the chi-square test to define associated factors and used binomial logistic regression analysis to determine the unconfounded predictors of IV. Results: The rate of IV among HCWs ranged from 53.3% during 2016 to 51.7% during the 2018 season. Compliances to successive vaccination over the past three years were only 30.2%; however, 66.2% of HCWs intended to receive the vaccine during the upcoming season. The main reasons for IV uptake included self-protection against influenza (60.7%) and caring about client's patients (44.8%). Single female nurses were more likely to be immunized against IV than other HCWs p<0.05. Both reading the official MOH IV guidelines and feeling of having sufficient knowledge about IV were unconfounded predictors for the vaccine. Conclusion: The overall immunization coverage was suboptimal, and the fact that reading the official MOH IV guidelines had a strong statistical association with a positive attitude towards vaccination emphasizes the role of governmental authorities in enhancing vaccine among the HCWs.

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Background: Influenza is a substantial threat to healthcare settings, and the annual influenza vaccine (IV) is an effective preventive measure against influenza. However, the vaccination rate among health care workers (HCWs) remains low. Objective: This study aimed at assessing vaccine coverage among HCWs at the primary health care centers of the Saudi Ministry of Health (MOH), and determine factors affecting compliance to vaccination. Methods: We conducted a cross-sectional study, and by applying a multistage clustering sample method, we randomly selected 83 male and 202 female HCWs. We used a self-administered questionnaire to collect information about IV uptake and its determinants. We performed the chi-square test to define associated factors and used binomial logistic regression analysis to determine the unconfounded predictors of IV. Results: The rate of IV among HCWs ranged from 53.3% during 2016 to 51.7% during the 2018 season. Compliances to successive vaccination over the past three years were only 30.2%; however, 66.2% of HCWs intended to receive the vaccine during the upcoming season. The main reasons for IV uptake included self-protection against influenza (60.7%) and caring about client's patients (44.8%). Single female nurses were more likely to be immunized against IV than other HCWs p<0.05. Both reading the official MOH IV guidelines and feeling of having sufficient knowledge about IV were unconfounded predictors for the vaccine. Conclusion: The overall immunization coverage was suboptimal, and the fact that reading the official MOH IV guidelines had a strong statistical association with a positive attitude towards vaccination emphasizes the role of governmental authorities in enhancing vaccine among the HCWsBackground: Influenza is a substantial threat to healthcare settings, and the annual influenza vaccine (IV) is an effective preventive measure against influenza. However, the vaccination rate among health care workers (HCWs) remains low. Objective: This study aimed at assessing vaccine coverage among HCWs at the primary health care centers of the Saudi Ministry of Health (MOH), and determine factors affecting compliance to vaccination. Methods: We conducted a cross-sectional study, and by applying a multistage clustering sample method, we randomly selected 83 male and 202 female HCWs. We used a self-administered questionnaire to collect information about IV uptake and its determinants. We performed the chi-square test to define associated factors and used binomial logistic regression analysis to determine the unconfounded predictors of IV. Results: The rate of IV among HCWs ranged from 53.3% during 2016 to 51.7% during the 2018 season. Compliances to successive vaccination over the past three years were only 30.2%; however, 66.2% of HCWs intended to receive the vaccine during the upcoming season. The main reasons for IV uptake included self-protection against influenza (60.7%) and caring about client's patients (44.8%). Single female nurses were more likely to be immunized against IV than other HCWs p<0.05. Both reading the official MOH IV guidelines and feeling of having sufficient knowledge about IV were unconfounded predictors for the vaccine. Conclusion: The overall immunization coverage was suboptimal, and the fact that reading the official MOH IV guidelines had a strong statistical association with a positive attitude towards vaccination emphasizes the role of governmental authorities in enhancing vaccine among the HCWs.

OPTIMIZE THE PROCESS PARAMETERS OF ROLLER COMPACTION STABLE AND ROBUST DOSAGE FORM: A REVIEW

Sujeet Kumar Das*, Praveen Kumar, Vikash Jakhmola
Department of Pharmacy , GRD (PG) IMT, Dehradun-248 009 Uttarakhand, India.

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Roll compaction is a unit process in the dry compaction process; a force enhances a mass procedure in which granules are ready with suitable flowability, granulation properties, chemical stability and uniformity especially for heat sensitive and moisture formulations. Throughout the roll compaction process, the active ingredient and excipients of the dry powders, example lubricants, diluents, binders and disintegrants are mixed in the blender. The mixtures of powder are then roller granulated and reduces the size to make granules. The resultant granules are blended with lubricated and compressed into a tablet form. The current work was undertaken to prepare a stable and robust dosage form by optimizing the process parameters of roll- compaction. In roller compaction powder blend is first passed through feeding sector, then densified powder go through compaction sector between two counter rotary rolls and sheets are formed. Granules are passed through a suitable sieve and oversize & undersize granules are separated. New compaction cycle is performed if the suitable ratios of oversize and undersize granules are not achieved. Then these granules are blended and extragarnular substance is blended with previous blend. Blend is then subjected to compression for tablet preparation. Sheets are evaluated for their breaking force by using Universal Force Tester® FMT 310. A sheet piece of 10 x 10 mm was placed in the test plate and the upper stamp was driven down towards the sheet with 10 mm/min of speed and breaking force is measured. The tablets made from roll compacted granules were found to be superior quality and all test revealed that evaluation parameters were under pharmacopoeial limits. With technological advances in drug development, dry granulation by roller compaction is more advantageous than wet granulation process with simple manufacturing process, low operational cost, no use of liquid solvent, large scale production and suitability for heat and moisture sensitive drug. objectives of the review article are to optimize the process parameters (Roll Compaction), optimize the blending parameters, perform the blend uniformity, evaluate the in-process parameters, and perform the dissolution study.

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Roll compaction is a unit process in the dry compaction process; a force enhances a mass procedure in which granules are ready with suitable flowability, granulation properties, chemical stability and uniformity especially for heat sensitive and moisture formulations. Throughout the roll compaction process, the active ingredient and excipients of the dry powders, example lubricants, diluents, binders and disintegrants are mixed in the blender. The mixtures of powder are then roller granulated and reduces the size to make granules. The resultant granules are blended with lubricated and compressed into a tablet form. The current work was undertaken to prepare a stable and robust dosage form by optimizing the process parameters of roll- compaction. In roller compaction powder blend is first passed through feeding sector, then densified powder go through compaction sector between two counter rotary rolls and sheets are formed. Granules are passed through a suitable sieve and oversize & undersize granules are separated. New compaction cycle is performed if the suitable ratios of oversize and undersize granules are not achieved. Then these granules are blended and extragarnular substance is blended with previous blend. Blend is then subjected to compression for tablet preparation. Sheets are evaluated for their breaking force by using Universal Force Tester® FMT 310. A sheet piece of 10 x 10 mm was placed in the test plate and the upper stamp was driven down towards the sheet with 10 mm/min of speed and breaking force is measured. The tablets made from roll compacted granules were found to be superior quality and all test revealed that evaluation parameters were under pharmacopoeial limits. With technological advances in drug development, dry granulation by roller compaction is more advantageous than wet granulation process with simple manufacturing process, low operational cost, no use of liquid solvent, large scale production and suitability for heat and moisture sensitive drug. objectives of the review article are to optimize the process parameters (Roll Compaction), optimize the blending parameters, perform the blend uniformity, evaluate the in-process parameters, and perform the dissolution study.

ASSESSMENT OF CULTURE AND SENSITIVITY OF MICROORGANISMS WITH VARIOUS ANTIMICROBIAL AGENTS USED IN SURGERY DEPARTMENT IN A TERTIARY CARE HOSPITAL IN INDIA

Sanisha V Soman1*, Mahima Jose2, Deepa Koshy3, Abiya Susan Shibu4, Mrs. Nisha Pothen5
Department Of Pharmacology, Nazareth College Of Pharmacy, Othera, Thiruvalla.

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STUDY OF INTERACTION (COMPATIBILITY) AND EVALUATION OF SOLUBILITY OF ACETYL SALICYLIC ACID IN PRESENCE OF EXCIPIENT LYSINE

Shanthala H.K.* Dr. Jayaprakash H.V, Dr.S.J. Shankar
Sri Siddhartha Academy of Higher Education, Tumakuru.
Department of Chemistry, Sri Siddhartha Institute of Technology, Tumakuru.
Vivekananda College of Pharmacy, Bengaluru.

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SYNTHESIS OF AMIDES BY ACTIVATION OF CARBOXYLIC ACIDS USING PHOSPHONITRILIC CHLORIDE

Jitendra S. Pulle
Department of Chemistry, S.G.B. College, Purna (Jn.), Dist. Parbhani (M.S.), India.

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SYNTHESIS, CHARACTERIZATION AND ANTIHYPERTENSIVE ACTIVITY OF PYRIDAZINONE DERIVATIVES

Vikash Jakhmola¹, Sunil Jawla², Ravinesh Mishra³, Ranjeet singh¹
¹Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh, Saharanpur-247341, Uttar Pradesh, India
²Department of Pharmacy, GRD (PG) IMT, Dehradun-248009 Uttarakhand, India.
³School of Pharmacy and Emering Sciences, Baddi University of Emerging Sciecnes and Technology, Baddi (Solan)-173205, Himachal Pradesh, India.

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DEVELOPMENT AND VALIDATION OF ANALYTICAL METHODS FOR THE SIMULTANEOUS ESTIMATION OF ROSUVASTATIN AND ASPIRIN DOSAGE IN COMBINE DOSAGE FORM

Shubham D. Chaudhari, Sachin S. Rane, Prof. (Dr.) Rajesh Y. Chaudhari,Prof. (Dr.) Vijay R. Patil
Hon’ble Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur. Tal. Yawal Dist. Jalgaon Maharashtra. PIN- 425503.

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A REVIEW ON MUCOADHESIVE MICROSPHERES AS AN EFFICIENT DRUG DELIVERY SYSTEM

Syed Tazib Rahaman*, Joy Mukherjee
GITAM Institute of Pharmacy; GITAM (Deemed to be University); Visakhapatnam; India.

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A REVIEW ON SYNTHESIS AND BIOLOGICAL ACTIVITY OF SUBSTITUTED APIGENIN DERIVATIVES

Shyam R. Deshmukh, Krishna R. Gupta*, Atul T. Hemke, Milind J. Umekar
Department of Pharmaceutical Chemistry, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, 441002, India.

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SELECTION OF AN EFFICIENT INDIGENOUS ARBUSCULAR MYCORHIZAL FUNGUS FOR COFFEA ARABICA L. OF NILGIRI DISTRICT, TAMILNADU, INDIA.

S. Rajeshkumar^1*, M. C. Nisha²

¹Government Arts College, Udhagamandalam, The Nilgiris- 643006, Tamilnadu, India.

²Emerald Heights College for Women, Udhagamandalam, the Nilgiris- 643006, Tamilnadu, India.

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The present study was undertaken to screen and select an efficient Arbuscular Mycorrhizal Fungi and also to study its effect on growth, biomass and nutrition in Coffea arabica L. of Nilgiri District. A poly bag trial was conducted at Government Arts College, Ooty. Seven dominant native AM fungi Acaulospora scorbiculata, Gigaspora margarita, Glomus aggregatum, Glomus fasciculatum, Glomus geosporum, Glomus mosseae, and Scutellospora heterogama isolated from different coffee plantations of Nilgiris were tested for their symbiotic efficiency against coffee plants. The growth and biomass in 6 months, 10 months, 14 months and 18 months and nutrient level of 18 months seedlings of seven different AM fungi inoculated plants were recorded. In general, inoculated plants showed increased plant height, number of leaves and biomass compared to control plants without am fungi inoculum. The plant growth, biomass and nutrient were maximum in plants inoculated with Glomus mosseae followed by those inoculated with Glomus aggregatum. Considering the various parameters such as plant growth, biomass and nutritional status of the plant, it was observed that Glomus mosseae is the best AM symbiont for C. arabica L. used in this experiment. The present study was undertaken to screen and select an efficient Arbuscular Mycorrhizal Fungi and also to study its effect on growth, biomass and nutrition in Coffea arabica L. of Nilgiri District. A poly bag trial was conducted at Government Arts College, Ooty. Seven dominant native AM fungi Acaulospora scorbiculata, Gigaspora margarita, Glomus aggregatum, Glomus fasciculatum, Glomus geosporum, Glomus mosseae, and Scutellospora heterogama isolated from different coffee plantations of Nilgiris were tested for their symbiotic efficiency against coffee plants. The growth and biomass in 6 months, 10 months, 14 months and 18 months and nutrient level of 18 months seedlings of seven different AM fungi inoculated plants were recorded. In general, inoculated plants showed increased plant height, number of leaves and biomass compared to control plants without am fungi inoculum. The plant growth, biomass and nutrient were maximum in plants inoculated with Glomus mosseae followed by those inoculated with Glomus aggregatum. Considering the various parameters such as plant growth, biomass and nutritional status of the plant, it was observed that Glomus mosseae is the best AM symbiont for C. arabica L. used in this experiment.

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The present study was undertaken to screen and select an efficient Arbuscular Mycorrhizal Fungi and also to study its effect on growth, biomass and nutrition in Coffea arabica L. of Nilgiri District. A poly bag trial was conducted at Government Arts College, Ooty. Seven dominant native AM fungi Acaulospora scorbiculata, Gigaspora margarita, Glomus aggregatum, Glomus fasciculatum, Glomus geosporum, Glomus mosseae, and Scutellospora heterogama isolated from different coffee plantations of Nilgiris were tested for their symbiotic efficiency against coffee plants. The growth and biomass in 6 months, 10 months, 14 months and 18 months and nutrient level of 18 months seedlings of seven different AM fungi inoculated plants were recorded. In general, inoculated plants showed increased plant height, number of leaves and biomass compared to control plants without am fungi inoculum. The plant growth, biomass and nutrient were maximum in plants inoculated with Glomus mosseae followed by those inoculated with Glomus aggregatum. Considering the various parameters such as plant growth, biomass and nutritional status of the plant, it was observed that Glomus mosseae is the best AM symbiont for C. arabica L. used in this experiment. The present study was undertaken to screen and select an efficient Arbuscular Mycorrhizal Fungi and also to study its effect on growth, biomass and nutrition in Coffea arabica L. of Nilgiri District. A poly bag trial was conducted at Government Arts College, Ooty. Seven dominant native AM fungi Acaulospora scorbiculata, Gigaspora margarita, Glomus aggregatum, Glomus fasciculatum, Glomus geosporum, Glomus mosseae, and Scutellospora heterogama isolated from different coffee plantations of Nilgiris were tested for their symbiotic efficiency against coffee plants. The growth and biomass in 6 months, 10 months, 14 months and 18 months and nutrient level of 18 months seedlings of seven different AM fungi inoculated plants were recorded. In general, inoculated plants showed increased plant height, number of leaves and biomass compared to control plants without am fungi inoculum. The plant growth, biomass and nutrient were maximum in plants inoculated with Glomus mosseae followed by those inoculated with Glomus aggregatum. Considering the various parameters such as plant growth, biomass and nutritional status of the plant, it was observed that Glomus mosseae is the best AM symbiont for C. arabica L. used in this experiment.

STUDY OF RATIONAL PRESCRIBING PATTERN AND DRUG MANAGEMENT FOR GERIATRIC PATIENTS IN A TERTIARY CARE HOSPITAL

Dr. Beulah Milton, Kapil Subedi, Sakshi Khadka, Dr. Peter Kandel.
RRCOP, Bangalore.

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SELF-ASSEMBLED ULTRADEFORMABLE PHOSPHOLIPID VESICLES WITH EDGE ACTIVATORS FOR DELIVERY OF TRANSCUTANEOUS BIOACTIVES

Ms. Namita G. Narvekar*, Mr. Mayuresh R. Redkar, Ms. Namita S. Bhosale
¹Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, (MS), India, 416510.
²Yashwantrao Bhonsale College of D Pharmacy, Sawantwadi, (MS), India, 416510.

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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF DALFAMPRIDINE, IN BULK AND PHARMACEUTICAL DOSAGE FORM.

Rathod K.G.

Mangaldeep Institute of Pharmacy, Nipani, Aurangabad.

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