In the present Investigational work, fast dissolving tablets of Olmesartan were planned to be prepared with a purposeof facilitating administration to patients experiencing problems with swallowing and improving its poor oral bioavailability,to get better disintegration, dissolution rate and bioavailability. The fast dissolving tablet were prepared by direct compression method and are characterized for various quality control tests such as tablet hardness, friability, weight variation, drug content uniformity, disintegration and dissolution.ODTs that are prepared by conventional methods usually have insufficient hardness, as well as they usually lack fast disintegration properties in the oral cavity of patient. Therefore, a fast disintegrating tablet having good mechanical strength and with required DT that could be achieved by using direct compression for formulation of ODT. The ODT’s were prepared by using Crosspovidone, Crosscarmellose sodium and Sodium starch glycolate as superdisintegrants, sodium lauryl sulphate as surfactant, wetting agent and dissolution agentwhile microcrystalline cellulose and lactose were used as diluents. The tablet prepared by using Crosspovidone as superdisintegrantshow lesser DT as compared to CCS and SSG. Amongst all batches superdisintegrantsCrospovidone at 5%show lesser DT than other superdisintegrants, their efficiency was found in the order of CP >CCS >SSG.Batch F12 formulation containing MCC and Lactose as a diluent and 5% Crospovidone as Superdisintegrant show lesser disintegration time i.e.22.15 sec while batch FS2 containing 0.25 % SLS showed 15.28 Sec DT.