Stevia rebaudiana is known for not only its nutritional values but also for medicinal benefits. Stevia rebaudiana is one of member of the genus Stevia. In the era of synthetic medicine and excipients natural plants and their products can be used as sources of medicine & exciepients. Stevia rebaudiana is belongs to family Astaraceae. With varieties of chemical constituents stevia rebaudiana consist of antioxidants like flavonoids and various phenolics, essential oils, tannins, etc. It is a natural source of steviol glycosides, like rebaudioside A and a potential source of prebiotics, with promising beneficial immunomodulating activity. Stevia rebaudiana is natural sweetener & is about 300 times sweeter than table sugar. Nutritional value of Stevia rebaudiana is beneficial for both the geriatrics & pediatrics ones. Stevia shows antiseptic, antiglycemic, antimicrobial, antibacterial, anticancer activity & also be used in indigesion, stomach upset, heart burn, weight loss, etc. It is expected hope for diabetic people who have craze to eat sweet. The aim of this review article is to describe systematic information with detailed exploration of pharmacological properties of stevia rebaudiana which will provide a direction for further research.