Abstract
Since ancient times, plants have been an exemplary source of medicine and used in treatment of various human ailments. India has about 45,000 plant species and among them 800 plants have been claimed to possess antidiabetic properties. Research conducted in last few decades on plants mentioned in ancient literature or used traditionally for diabetes has shown anti-diabetic property. There is considerable need for safe agents that can reduce risk for diabetes in at-risk subjects. The reviews of various plants and their products (active, natural principles and crude extracts) mentioned/used in the Indian traditional system of medicine have shown experimental or clinical anti-diabetic activity. In present, Enicostemma littorale, Gymnema sylvestre and Momordica charantia have been reviewed for their antidiabetic and cardioprotective properties.