Welcome to Indo American Journal of Pharmaceutical Research

SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF ISONIAZID AND PYRIDOXINE

Anitha K*1, T. M. Kalyankar2, U. A. Khedkar2, R. B. Gholve2
1Department of Chemistry, Sri Krishnadevaraya University, Ananthapuram - 515003, Andhra Pradesh, India.

2School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded - 431606, Maharashtra, India.

Graphical Abstract

Abstract Article Highlights Download PDF (57) Google Scholar

ONE POT SYNTHESIS OF 1, 8- DIOXO -OCTAHYDROXANTHENES IN AQUASE PHASE USING ? - CYCLODEXTRIN AS AN EFFICIENT AND GREEN CATALYST

Shankar P Hangirgekar*, Vijay V Kumbhar,Navanand B Wadwale
School of Chemical Sciences, S.R.T.M.University, Nanded-431606, Maharashtra India.

Graphical Abstract

Abstract Article Highlights Download PDF (11) Google Scholar

PHYTONUTRIENT COMPOSITION AND ANTIOXIDANT ACTIVITY OF PROCESSED FLAXSEED

Dharshini¹, Dr.S.Sumayaa², Dr.T.Thirunalasundari ³

¹Research Scholar, Department of Food Science and Nutrition, Thassim Beevi Abdul Kader College for Women, Kilakarai, Tamil Nadu, India.

²Head of the Department, Department of Biotechnology, Bharathidasan University, Tiruchirappali, Tamil Nadu, India.

³Principal, Thassim Beevi Abdul Kader College for Women, Kilakarai, Tamil Nadu, India.

Graphical Abstract

Abstract

Flax is a nutraceutical with many nutritional benefits. Aside from the vitamins, minerals, fiber and protein it contains some primary and secondary metabolites. Flaxseed is a good source of omega-3 fatty acids. Through its high concentration of alpha-linolenic acid, flax provides more omega-3 fatty acids than any other grain. (57% of its fatty acids are omega-3s.) As the health revolution continues to evolve, look for it to be added to more and more processed foods to attain the health smart claim. Flaxseed (FS), a whole grain used as a nutritional supplement, has gained popularity because it is a rich source of natural antioxidants. Dietary intake of polyphenols has been associated to reduce risk of chronic diseases, such as heart disease, stress induced diabetes and cancer. This is probably due to their antioxidant properties. Many phenolic compounds have been detected in Flaxseed. Hence with the objectives to analyze the phytonutrient composition, assess the non-antioxidant enzymes vitamin A, E and C and find the antioxidant activity of processed flaxseed the study was carried out. The flaxseed was subjected to various methods of food processing like roasting, pressure cooking and soaking. The processed flaxseed was further analysed the primary and secondary metabolites and their antioxidants activity. This study does not show much variation in primary and secondary metabolites between the raw and roasted seeds. The acceptance and palatability was high in the case of roasted soybean and flaxseed because of their nutrients nutty flavour, colour and texture than the unprocessed seeds. Non- antioxidant enzymes, vitamin A, vitamin E and vitamin C content was high in both soaked and roasted flaxseed. Antioxidant activity was high in roasted and soaked flaxseed. Thus the presence of these phytonutrient and antioxidant activity of processed namely roasted and soaked flaxseeds indicates that, it has a potential of being used in formulations prepared for food consumption. Flaxseed could also be a remedy for the major killer diseases like cancer, diabetes and cardiovascular diseases.

Article Highlights

The file does not exist in any folder.

Google Scholar

BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF LOSARTAN IN RABBIT PLASMA BY RP-HPLC

Sandhya Pamu*^1,2, Subrahmanyam C V S², Rao Patnaik K S K¹

¹Department of Pharmacy,University College of Technology, Osmania University, Hyderabad 500 007, India.

²Gokaraju Rangaraju College of Pharmacy College, Bachupally, Hyderabad 500090, Telangana State, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

DIPEPTIDYL PEPTIDASE-4 INHIBITORS: THEIR ROLE IN THE MANAGEMENT OF TYPE 2 DIABETES

P. Sujatha*, S. Vijaya

Rajiv Gandhi Institute of Medical Sciences, Srikakulam.

Graphical Abstract

Abstract

Abstract

A primary objective in the management of type 2 diabetes, optimal glycaemic control is difficult to achieve and usually not maintained over time. Type 2 diabetes is a complex pathology, comprising altered insulin sensitivity and impaired insulin secretion. Recent advances in the understanding of the physiological functions of incretins and their degrading enzyme dipeptidyl-peptidase (DPP)-4 have led to the ‘discovery’ of a new class of oral anti-diabetic drugs. Several DPP-4 inhibitors (or gliptins) with different chemical structures are now available. These agents inhibit the degradation of the incretins. glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) and hence potentiate glucose-dependent insulin secretion. DPP-4 inhibitors inhibit DPP-4 activity by almost 100% in vitro, maintaining a >80% inhibition throughout the treatment period in vivo, thus prolonging GLP-1 half-life, and significantly reducing HbA1c generally by -0.7 – 0.8% as well as fasting and postprandial glycaemia. They are well-tolerated with no weight gain and few adverse effects, and, of particular interest, no increase in hypoglycaemic episodes. Although different by their chemical structure and pharmacokinetic properties, the DPP4 inhibitors currently available have proven similar glucose lowering efficacy. The production of glucagon-like peptide 1 (GLP-1), an incretin hormone, has been shown to be abnormally low in patients with type 2 diabetes, suggesting that GLP-1 may be a contributor in the pathogenesis of the disease. New type 2 diabetic medications target incretin hormones in their mechanism of action. The incretin effect is based on the understanding that oral glucose has a greater stimulatory effect on insulin secretion than that of intravenous glucose. Over the past few years, a number of therapeutic agents, acting either as incretin mimetics, e.g. GLP-1 agonists, or inhibitors of the breakdown of GLP- 1, e.g. dipeptidyl peptidase-4 inhibitors, have become available as treatment options for the management of type 2 diabetes.

Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

Abstract

DEVELOPMENT, CHARACTERISATION AND EVALUATION OF SILDENAFIL ASPIRIN CO-CRYSTALS

Avani P. Khristi, Dr.Tejal Soni, Dr. B.N.Suhagia

Faculty of Pharmacy/ Dharmsinh Desai University, Nadiad- Gujarat.

Graphical Abstract

Abstract

Abstract

Sildenafil citrate is a selective inhibitor of phosphodiesterase type 5 enzyme (PDE5) extensively used for the treatment of erectile dysfunction (ED). Sildenafil citrate is BCS class II drug, practically insoluble in water. It’s absolute bioavailability is 41% and half life is 4 hours. Aspirin is a Cyclooxygenase Inhibitors (COX-1 & COX-2) having a mechanism by dilating blood vessels in vivo, probably through direct effect on vascular smooth muscle. Therefore, the vasodilator action of aspirin which dilates the blood vessels gives synergistic effect to Sildenafil Citrate. The active pharmaceutical ingredients (APIs) in crystalline forms are more promising towards the stability, reproducibility and purification of the same in comparison to other types of solid forms, hence having the most priority in comparison to other forms. The properties like dissolution rate and intrinsic solubility of several crystalline forms are different and thus are playing an important role in enhancing the bioavailability. The stability with respect to temperature and humidity are more significantly depending on packaging of crystals. Sildenafil Aspirin Pharmaceutical co-crystals were successfully engineered with succinic acid as coformer under reflux condition. A new solid phase (cocrystals) was characterized by Fourier transformation infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), powder X-ray diffractometry (PXRD). Physical characterization showed that Sildenafil Aspirin cocrystalline phase had unique thermal, powder X-ray diffraction property. The physicochemical properties of pure Sildenafil and corresponding co-crystals were accessed in terms of melting point, drug content uniformity, dissolution studies. The rapid rate of dissolution of cocrystals was observed in initial 10 min. The extent of dissolution was also enhanced on account of cocrysatllization.

Article Highlights Download PDF (65) Zenodo DOI Google Scholar

DOI Link

Abstract

AN IMPROVED PROCESS FOR PREPARATION OF PALIPERIDONE PALMITATE, AN ANTI-PSYCHOTIC AGENT

N. V. D. Harikiran Maddi, ^1,2 Suribabu Madasu,^1,2 N.A.Vekariya,¹ Koteswaramma Ch,¹ T. Chandiran,¹ Aminul Islam,¹ Paul S Douglas,² Korupolu Raghubabu²

¹Chemical Research and Development, Aurobindo Pharma Ltd.,Survey No.71&72,Indrakaran (V), Sangareddy (M), Medak Dist 502329. Telangana State, India.

²Engineering Chemistry Department, AU College of Engineering, Andhra University, Visakhapatnam-530003, Andhra Pradesh, India.

Graphical Abstract

Abstract Article Highlights Download PDF (112) Zenodo DOI Google Scholar

DOI Link

IN SILICO ADME AND BIOACTIVITY PREDICTION OF PHYTOCONSTITUENTS OF MORINGA OLEIFERA AGAINST ALZHEIMERS DISEASE

Lalit Rajan Samant, Vikrant Chandakant Sangar, Anuya Rege, Shahid Chowdhary, Sandip Pawar, Abhay Chowdhary Haffkine

Institute for Training Research and Testing.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

DISSOLUTION RATE ENHANCEMENT OF PIOGLITAZONE BY SOLID DISPERSION TECHNIQUE

Prabhjot Kour¹, Mahesh Kumar Kataria², Ajay Bilandi³

¹Student, M. Pharmacy 4th Semester (Pharmaceutics), Seth G.L. Bihani S.D. College of Technical Education, Sri Ganganagar.

²Professor and Head of Department (Pharmaceutics), Seth G.L. Bihani S.D. College of Technical Education, Sri Ganganagar.

³Assistant Professor, Seth G.L. Bihani S.D. College of Technical education, Sri Ganganagar.

Graphical Abstract

Abstract Article Highlights Download PDF (94) Zenodo DOI Google Scholar

DOI Link

SIDE EFFECTS OF AYURVEDIC MEDICINES

Ms. Shruti B. Patil, Ms. Vaibhavi N. Garge, Dr. Vilasrao J. Kadam

Department of Pharmacology and Toxicology, Bharati Vidyapeeth’s College of Pharmacy, C. B. D. Belapur, Navi Mumbai-400614, Maharashtra, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

FORMULATION & EVALUATION OF GASTRIC FLOATING DRUG DELIVERY SYSTEM OF METOPROLOL SUCCINATE

Monica.G*, V.Vasu Naik, A. Anka Rao, A. Rajesh

Hindu College of Pharmacy, Amaravathi Road,Guntur, Andhra Pradesh, India.

Graphical Abstract

Abstract Article Highlights Download PDF (80) Zenodo DOI Google Scholar

DOI Link

SPECTROPHOTOMETRIC SIMULTANEOUS DETERMINATION OF LAMIVUDINE, TENOFOVIR AND NEVIRAPINE IN COMBINED TABLET DOSAGE FORM BY RATIO DERIVATIVE AND FIRST ORDER DERIVATIVE METHOD

G. D. Biradar, S. N. Deshpande, *V. P. Choudhari

Department of Pharmaceutical Analysis and Quality Assurance, MAEER’S Maharashtra Institute of Pharmacy, Kothrud, Pune-411038.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

A STUDY TO ASSESS MEDICATION ADHERENCE TOWARDS ANTI DIABETIC THERAPY IN PATIENTS DIAGNOSED WITH TYPE 2 DIABETES MELLITUS OF DAVANGERE, KARNATAKA

Dr. Baishnab S^3*, Dr. Basavarajappa A P², Sushilkumar P L^3,4, Morla S¹, Patel Y A¹, Kukadiya A G¹, Chaitanya Kumar T³, Muneerudeen J³

¹ Intern, Department of Pharmacy Practice, Bapuji Pharmacy College, Davangere, Karnataka.

² Principal, Bapuji Pharmacy College, Davangere, Karnataka.

³ Lecturer, Department of Pharmacy Practice, Bapuji Pharmacy College, Davangere, Karnataka.

⁴ Research Scholar, R K University, Rajkot, Gujarat.

Graphical Abstract

Abstract Article Highlights Download PDF (67) Zenodo DOI Google Scholar

DOI Link

DEVELOPMENT AND IMPLEMENTATION OF A DRUG FORMULARY FOR THE MEDICINE DEPARTMENT OF TERTIARY CARE TEACHING HOSPITAL

Sushilkumar P L^2*,3, Dr. Baishnab S², Johnson G¹, John J A¹, Philip L A¹, Philip M S¹, Chaitanya Kumar T², Dr. Sam G K²

¹ Intern, Department of Pharmacy Practice, Bapuji Pharmacy College, Davangere, Karnataka.

² Lecturer, Department of Pharmacy Practice, Bapuji Pharmacy College, Davangere, Karnataka.

³ Research Scholar, R K University, Rajkot, Gujarat.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

SPECTRAL AND ANTIBACTERIAL STUDIES ON SOME ETHNOBOTANICALLY IMPORTANT MEDICINAL PLANTS USED BY THOTTIANAICKANS OF SEMMALAI

Thiravia Doss Dons, Sebastian Soosai Raj*

Department of Botany, St. Joseph’s College, Tiruchirappalli – 620002, Tamilnadu, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

ETHNIC KNOWLEDGE OF DYE YIELDING PLANTS USED BY THE KANI TRIBES OF PONMUDI HILL: A CASE STUDY

Bosco Lawarence, S Mahesh, Aswathy J M, Greeshma Murugan, K. Murugan

Plant Biochemistry and Molecular Biology Laboratory, Department of Botany, University College, Trivandrum 695 034, India.

Graphical Abstract

Abstract

Abstract

Dyes are the natural or artificial chemicals used to add colour to materials. Most of the natural dyes are made from plant parts such as leaves, flowers, roots, berries, bark, rhizomes, tubers, shoots, sap and wood. Textile dyeing dates back to the Neolithic period. The present work is the first comprehensive account of the dye yielding plant diversity of Ponmudi hills, a part of Western Ghats being utilised by the Kani tribes including local inhabitants. A survey has been done on the ethnic use of dye yielding plants with its utility values. Pterocarpus marsupium Roxburgh (Fabaceae), Woodfordia furticosa Kurz (Lythraceae), Terminalia paniculata (Roxb.) Wight & Arn. (Combretaceae), Morinda citrifolia Linn. (Rubiaceae), Clitoria ternatea Linn. (Fabaceae), Butea monosperma Taub. (Fabaceae), Butea superba Roxb. Ex Willd. (Fabaceae), Pandanus odorifer (Forssk.) Kuntze (Pandanaceae), Carthamus tinctorius L. (Asteraceae), Diospyros paniculata Dalz. (Ebenaceae), Cordia dichotoma Forst. (Boraginaceae), Nyctanthes arbor-tristis Linn (Oleaceae), Curcuma aromatica Salisb. (Zingiberaceae), Tectona grandis Linn.f (Verbenaceae) and many Osbeckia species such as O. aspera, O. reticulata, O. wynadensis and O. parviflora are the most common dye plants used by the people for multi purposes. The dyeing parts of the plants are used by the ethnic communities for various religious purposes. Further, they are confident regarding the non toxic and eco-friendly nature of the natural dye. However, the indigenous information, practice of extraction and processing of natural dyes has now declined due to readily available cheaper synthetic dyes. It is high time that proper documentation and conservation of this knowledge to conserve these natural dye plants. Osbeckia species being promising in this line, further studies are designed to analyze the major phytochemicals like anthocyanin and its biological characterization.

Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

Abstract

AN ASSAY METHOD FOR THE SIMULTANEOUS ESTIMATION OF ACETAMINOPHEN AND TRAMADOL USING RP-HPLC TECHNOLOGY

Fayeza Batool*, Osman Ahmed, Anas Rasheed

Department of Pharmaceutical Analysis & Quality Assurance, Deccan School of Pharmacy, Hyderabad, T.S.

Graphical Abstract

Abstract Article Highlights Download PDF (70) Zenodo DOI Google Scholar

DOI Link

INCIDENCES OF LOOSE SHELL SYNDROME (LSS) IN CULTURED LITOPENAEUS VANNAMEI, ANDHRA PRADESH

S.A. Mastan

P V S Laboratories Limited, Aqua Division, Kohinoor Apartments, Kalanagar, Benz Circle, Vijayawada-520 010, Andhra Pradesh, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

EFFECTS OF PARACETAMOL-INDUCED LIVER DAMAGE ON SOME HEMATOLOGICAL PARAMETERS: RED BLOOD CELL (RBC) COUNT, WHITE BLOOD CELL (WBC) COUNT, AND PACKED CELL VOLUME (PCV) IN WISTAR RATS OF EITHER SEX

*Seriki A. Samuel, Adebayo O. Francis, Oshagbemi Ayomide, Uche-Orji Onyinyechi

Department of Physiology, Faculty of Medical Sciences Bingham University, Karu, Nigeria.

Graphical Abstract

Abstract Article Highlights Download PDF (90) Zenodo DOI Google Scholar

DOI Link

EVALUATION OF BETA BLOCKERS USE AT A TERTIARY CARE HOSPITAL

Sukesh Krishna Chaitanya Loka^*, Vinuthna Yashki, Alekhya Vissampally, Divya Jose

Malla Reddy Institute of Pharmaceutical Sciences, Hyderabad.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

ANTIBACTERIAL AND ANTIOXIDANT POTENTIAL OF METHANOLIC LEAF EXTRACT OF PUTRANJIVA ROXBURGHII WALL

Dr.Narendra Kumar

Senior Lecturer, Amity Institute of Biotechnology, Amity University Haryana, Manaser-122413, Gurgaon, Haryana, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

ANTIOXIDANTS: MIRACLE FOR AGE AND AGE RELATED DISORDERS

Palak Landge*, Stuti Dave, Abhishek Jagani, Ruchit Patel

Department of Pharmaceutical Chemistry, Babaria Institute of Pharmacy, Varnama, Vadodara, Gujarat, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

FORMULATION AND EVALUATION OF FAST DISSOLVING METRONIDAZOLE TABLET

Subahan Ali¹, Berpal Sing¹, K K Jha² and Arkendu Chatterjee*¹

¹Department of Pharmaceutics, Teerthankar Mahaveer University,Moradabad, Uttarpradesh, India.

²Department, of Pharmaceutical Chemistry, Teerthankar Mahaveer University, Moradabad, Uttarpradesh, India.

Graphical Abstract

Abstract

Abstract

The oral estimation structures are the most common system for taking medication despite having a couple weights like moderate maintenance and along these lines onset of movement is drag out. This can be overcome by administrating the prescription in liquid from in the mean time, various APIs have compelled level of dauntlessness in liquid structure. In this way, Effervescent Tablets goes about as a choice estimations structure. The present work is taking into record the arrangement of gurgling granules of metronidazole ie F1 to F4. Four arrangements were prepared using particular, diluents and superdisintegrants by the wet granulation procedure. The prepared tablets of all the formulations were evaluated for precompression parameters like angle of repose, bulk density, tapped density and compressibility index and physical characters like tablet hardness, friability, weight variation, buoyancy lag time. The formulations showed good flow property and Carr’s index. Angle of repose ranged from 30±1.020 to 34±2.390, Carr’s index ranged from 4.0±0.62 to 6.25±1.12 and the Hausner ratio ranged from 1.0±1.14 to 1.06±2.29. The state of tablets of all definitions stayed white, smooth, curved confronted round with no unmistakable splits. The thickness of tablets was extended between 2.44±2.11mm to 3.56±1.56mm separately. The hardness of the tablets found in between 5.2±1.29to 6.4±1.34kg/cm2. The friability was discovered to be 4.34±1.07 % to 6.38±1.91%, which is a sign of palatable mechanical resistance of the tablets. The medication content estimations demonstrated values in the scope of 95.8% to 99.2% which reflects great consistency in medication content among distinctive definitions. Every one of the tablets breezed through weight variety test as the % weight variety was 8.11±0.76 to 9.86±1.54mg and effervescent time shown 6±2.13 to 10±1.45 second. Out of that we wear optimized formulation was F2.

Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

Abstract

QUALITY OF SLEEP AMONG TUBERCULOSIS PATIENTS- A PILOT STUDY

Ahamada Safna Mariyam. M*¹, Sudhakar. R², Yasaswini Bandlamudi², Suhas Reddy .C³

¹Assistant Professor, Department of Pharmacy Practice, Acharya & B.M Reddy College of Pharmacy, Bangalore, India.

²Pharm.D Interns, Nandha College of Pharmacy, Erode, India.

³Lecturer, Department of Pharmacy Practice, Acharya & B.M Reddy College of Pharmacy, Bangalore, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

PRESCRIBING PATTERNS OF ANALGESICS IN THE POST-OPERATIVE PERIOD OF SURGICAL INTERVENTIONS

Allam Roshini, A. Siva Abhishek, K. Ashwini, J. Manasa , Mohd.Tahir Siddiqui

Department of Pharmacy Practice, Malla Reddy College of Pharmacy, Maisammaguda, Secundrabad, Telangana.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

EVALUATION OF ANTI-CANCER ACTIVITY DOLICHANDRONE ATROVIRENS IN EXPERIMENTAL INDUCED ANIMAL MODEL

P. Natarajan*¹, R. Arunpandian²

¹Sankaralingm Bhuvaneswari College of Pharmacy, 3/77-c Anaikuttam Road, Anaikuttam, Sivakasi, Tamil Nadu, India.

²Micro Therapeutics, Coimbatore, Tamil Nadu.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

A STUDY OF INTRAVENOUS DROTAVERINE Hcl Vs VALETHAMATE BROMIDE ON DURATION OF LABOR

Dr. U. Agnes Vijaya¹*, Purushothama Reddy. K², A. Nagaraju³, Mallesh. M³

¹Associate Professor, MD, D.G.O, Department of Obstetrics & Gynaecology, RIMS, Kadapa, India.

²Assistant Professor, Department of Pharmacy Practice, P. Rami Reddy Memorial College of Pharmacy, Kadapa, India.

³Pharm.D Interns, Department of Pharmacy Practice, P. Rami Reddy Memorial College of Pharmacy, Kadapa, India.

Graphical Abstract

Abstract Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

PHYSICO-CHEMICAL AND PHYTOCHEMICAL STUDY OF HYDROETHANOLIC PETAL EXTRACT OF PINK NELUMBO NUCIFERA GAERTN

Saraswathi RV, Gricilda Shoba F*

P.G. & Research Department of Zoology, Voorhees College, Vellore - 632009, Tamilnadu, India.

Graphical Abstract

Abstract

Abstract

Nature has given rise to medicinal agents for thousands of years. Various medicinal plants have been used for years in daily life to treat the disease all over the world. The therapeutic use of herbs is as old as human civilization and has evolved along with it. Medicinal plant drug discovery continues to provide new and important leads against various effects like cancer, malaria, cardiovascular diseases and neurological disorders. Interest in herbal drugs and natural medicine is undergoing a renaissance now. The curative properties of plants are due to the presence of active principles such as alkaloids, phenolics, tannins and flavonoids that constitute of many pharmacologically active compounds. The aim of the present study was to know about the physico-chemical evaluation of the extract, phytochemical screening and quantification of primary and secondary metabolites in the Nelumbo nucifera petal extract. The results obtained in the present study reveal the following: physico-chemical parameters show a good result in Nelumbo nucifera petal extract and can be used for the formulation of the drug. phytochemical screening and quantification of primary and secondary metabolites in the Nelumbo nucifera petal extract shows the presence of primary metabolites viz., carbohydrates, proteins and lipids and the secondary metabolites such as tannins, phenols flavonoids and alkaloids on phytochemical screening. Quantification of primary metabolites of the extract shows its nutritive value and the secondary metabolites were responsible for its medicinal properties of the petals of the Nelumbo nucifera Gaertn that was used by the traditional herbalists. Finally, the present finding of the study concludes, that the hydro ethanolic Nelumbo nucifera petal extract possess abundant phytochemicals, which act as a source of natural antioxidants having a great importance in preventing various diseases and further study was needed to find out the active principle present in the Nelumbo nucifera petals.

Article Highlights Download PDF (72) Zenodo DOI Google Scholar

DOI Link

Abstract

FORMULATION AND EVALUATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE (160/25MG) FILM COATED TABLETS

Shailesh Sharma, Tanusha Kapoor

Department of Pharmaceutical Research Divison ASBASJSM College of Pharmacy, BELA (Ropar), Punjab 140111 India.

Graphical Abstract

Abstract Article Highlights Download PDF (63) Zenodo DOI Google Scholar

DOI Link

ACNE-CAUSES AND AMAZING REMEDIAL MEASURES FOR ACNE

P. Ravisankar*¹, O. Sai Koushik¹, V. Himaja¹, J. Ramesh¹, P. Pragna²

¹Department of Pharmaceutical Analysis and Quality Assurance, Vignan Pharmacy College, Vadlamudi, Guntur (Dist.) - 522213, Andhra Pradesh State, India. ²Malla Reddy Medical College for Women, Jeedimetla, Hyderabad-500055, Telangana State, India.

Graphical Abstract

Abstract

Abstract

The word acne comes from the word acme meaning "the highest point," which comes from the Greek akme meaning “point or spot”. In the entire world 650 million people with acne have been suffering, which is about 9.4 % of the world population out of which females are 9.8 % men amounting to 9.0 % which indicates females are more prone to this acne disease .It attracts nearly 40 to 50 million population in the United States (16 %) and more or less 3 to 5 million people in Australia (23 %). Acne is most common skin disease. Acne effects all races and ages and became the most common skin disease, especially in teenagers and young adults. It is estimated approximately 90 % out of age group between 11 and 30 are being attacked by acne outbreaks and during puberty in both sexes, acne can born owing to an increase in androgens such as testosterone and 90 % are suffering from acne at puberty stage all over the globe. Nearly 80 % out of age group of 11 to 30 year-olds are the sufferers with acne at any time of this stage basing on their physiological condition of their body and some people in their age at 40s and 50s still get acne disease. Acne is one of the greatest skin problems faced by adults. As many as 25 percent of all adult men and 50 percent of adult women suffer from acne disease at some point in their life. But adult acne can be particularly frustrating. Research shows 35 % of women in their 30s, 26 % in their 40s, and 15 % age 50 + are the sufferers from acne disease. Women over the age of 33 are more likely to get premenstrual pimples than younger women. The chief ground for this disease is the bad environment, eating an inflammatory diet or living a sedentary lifestyle or both can contribute to the underlying cause of acne. The information on this article can help to understand acne, types of acne, causes for development of acne treatment and home remedies and treatment.

Article Highlights

The file does not exist in any folder.

Zenodo DOI Google Scholar

DOI Link

Abstract

SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF ISONIAZID AND PYRIDOXINE

Graphical Abstract

ONE POT SYNTHESIS OF 1, 8- DIOXO -OCTAHYDROXANTHENES IN AQUASE PHASE USING ? - CYCLODEXTRIN AS AN EFFICIENT AND GREEN CATALYST

Graphical Abstract

PHYTONUTRIENT COMPOSITION AND ANTIOXIDANT ACTIVITY OF PROCESSED FLAXSEED

Graphical Abstract

BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF LOSARTAN IN RABBIT PLASMA BY RP-HPLC

Graphical Abstract

DIPEPTIDYL PEPTIDASE-4 INHIBITORS: THEIR ROLE IN THE MANAGEMENT OF TYPE 2 DIABETES

Graphical Abstract

DEVELOPMENT, CHARACTERISATION AND EVALUATION OF SILDENAFIL ASPIRIN CO-CRYSTALS

Graphical Abstract

AN IMPROVED PROCESS FOR PREPARATION OF PALIPERIDONE PALMITATE, AN ANTI-PSYCHOTIC AGENT

Graphical Abstract

IN SILICO ADME AND BIOACTIVITY PREDICTION OF PHYTOCONSTITUENTS OF MORINGA OLEIFERA AGAINST ALZHEIMERS DISEASE

Graphical Abstract

DISSOLUTION RATE ENHANCEMENT OF PIOGLITAZONE BY SOLID DISPERSION TECHNIQUE

Graphical Abstract

SIDE EFFECTS OF AYURVEDIC MEDICINES

Graphical Abstract

FORMULATION & EVALUATION OF GASTRIC FLOATING DRUG DELIVERY SYSTEM OF METOPROLOL SUCCINATE

Graphical Abstract

SPECTROPHOTOMETRIC SIMULTANEOUS DETERMINATION OF LAMIVUDINE, TENOFOVIR AND NEVIRAPINE IN COMBINED TABLET DOSAGE FORM BY RATIO DERIVATIVE AND FIRST ORDER DERIVATIVE METHOD

Graphical Abstract

A STUDY TO ASSESS MEDICATION ADHERENCE TOWARDS ANTI  DIABETIC THERAPY IN PATIENTS DIAGNOSED WITH TYPE 2 DIABETES MELLITUS OF DAVANGERE, KARNATAKA

Graphical Abstract

DEVELOPMENT AND IMPLEMENTATION OF A DRUG FORMULARY FOR THE MEDICINE DEPARTMENT OF TERTIARY CARE TEACHING HOSPITAL

Graphical Abstract

SPECTRAL AND ANTIBACTERIAL STUDIES ON SOME ETHNOBOTANICALLY IMPORTANT MEDICINAL PLANTS USED BY THOTTIANAICKANS OF SEMMALAI

Graphical Abstract

ETHNIC KNOWLEDGE OF DYE YIELDING PLANTS USED BY THE KANI TRIBES OF PONMUDI HILL: A CASE STUDY

Graphical Abstract

AN ASSAY METHOD FOR THE SIMULTANEOUS ESTIMATION OF ACETAMINOPHEN AND TRAMADOL USING RP-HPLC TECHNOLOGY

Graphical Abstract

INCIDENCES OF LOOSE SHELL SYNDROME (LSS) IN CULTURED LITOPENAEUS VANNAMEI, ANDHRA PRADESH

Graphical Abstract

EFFECTS OF PARACETAMOL-INDUCED LIVER DAMAGE ON SOME HEMATOLOGICAL PARAMETERS: RED BLOOD CELL (RBC) COUNT, WHITE BLOOD CELL (WBC) COUNT, AND PACKED CELL VOLUME (PCV) IN WISTAR RATS OF EITHER SEX

Graphical Abstract

EVALUATION OF BETA BLOCKERS USE AT A TERTIARY CARE HOSPITAL

Graphical Abstract

ANTIBACTERIAL AND ANTIOXIDANT POTENTIAL OF METHANOLIC LEAF EXTRACT OF PUTRANJIVA ROXBURGHII WALL

Graphical Abstract

ANTIOXIDANTS: MIRACLE FOR AGE AND AGE RELATED DISORDERS

Graphical Abstract

FORMULATION AND EVALUATION OF FAST DISSOLVING METRONIDAZOLE TABLET

Graphical Abstract

QUALITY OF SLEEP AMONG TUBERCULOSIS PATIENTS- A PILOT STUDY

Graphical Abstract

PRESCRIBING PATTERNS OF ANALGESICS IN THE POST-OPERATIVE PERIOD OF SURGICAL INTERVENTIONS

Graphical Abstract

EVALUATION OF ANTI-CANCER ACTIVITY DOLICHANDRONE ATROVIRENS IN EXPERIMENTAL INDUCED ANIMAL MODEL

Graphical Abstract

A STUDY OF INTRAVENOUS DROTAVERINE Hcl Vs VALETHAMATE BROMIDE ON DURATION OF LABOR

Graphical Abstract

PHYSICO-CHEMICAL AND PHYTOCHEMICAL STUDY OF HYDROETHANOLIC PETAL EXTRACT OF PINK NELUMBO NUCIFERA GAERTN

Graphical Abstract

FORMULATION AND EVALUATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE (160/25MG) FILM COATED TABLETS

Graphical Abstract

ACNE-CAUSES AND AMAZING REMEDIAL MEASURES FOR ACNE

Graphical Abstract

IN SILICO ADME AND BIOACTIVITY PREDICTION OF PHYTOCONSTITUENTS OF MORINGA OLEIFERA AGAINST ALZHEIMERS DISEASE

A STUDY TO ASSESS MEDICATION ADHERENCE TOWARDS ANTI DIABETIC THERAPY IN PATIENTS DIAGNOSED WITH TYPE 2 DIABETES MELLITUS OF DAVANGERE, KARNATAKA

QUALITY OF SLEEP AMONG TUBERCULOSIS PATIENTS- A PILOT STUDY

A STUDY OF INTRAVENOUS DROTAVERINE Hcl Vs VALETHAMATE BROMIDE ON DURATION OF LABOR