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SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF ISONIAZID AND PYRIDOXINE

Anitha K*1, T. M. Kalyankar2, U. A. Khedkar2, R. B. Gholve2
1Department of Chemistry, Sri Krishnadevaraya University, Ananthapuram - 515003, Andhra Pradesh, India.

2School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded - 431606, Maharashtra, India.

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PHYTONUTRIENT COMPOSITION AND ANTIOXIDANT ACTIVITY OF PROCESSED FLAXSEED

Dharshini¹, Dr.S.Sumayaa², Dr.T.Thirunalasundari ³

¹Research Scholar, Department of Food Science and Nutrition, Thassim Beevi Abdul Kader College for Women, Kilakarai, Tamil Nadu, India.

²Head of the Department, Department of Biotechnology, Bharathidasan University, Tiruchirappali, Tamil Nadu, India.

³Principal, Thassim Beevi Abdul Kader College for Women, Kilakarai, Tamil Nadu, India.

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Abstract

Flax is a nutraceutical with many nutritional benefits. Aside from the vitamins, minerals, fiber and protein it contains some primary and secondary metabolites. Flaxseed is a good source of omega-3 fatty acids. Through its high concentration of alpha-linolenic acid, flax provides more omega-3 fatty acids than any other grain. (57% of its fatty acids are omega-3s.) As the health revolution continues to evolve, look for it to be added to more and more processed foods to attain the health smart claim. Flaxseed (FS), a whole grain used as a nutritional supplement, has gained popularity because it is a rich source of natural antioxidants. Dietary intake of polyphenols has been associated to reduce risk of chronic diseases, such as heart disease, stress induced diabetes and cancer. This is probably due to their antioxidant properties. Many phenolic compounds have been detected in Flaxseed. Hence with the objectives to analyze the phytonutrient composition, assess the non-antioxidant enzymes vitamin A, E and C and find the antioxidant activity of processed flaxseed the study was carried out. The flaxseed was subjected to various methods of food processing like roasting, pressure cooking and soaking. The processed flaxseed was further analysed the primary and secondary metabolites and their antioxidants activity. This study does not show much variation in primary and secondary metabolites between the raw and roasted seeds. The acceptance and palatability was high in the case of roasted soybean and flaxseed because of their nutrients nutty flavour, colour and texture than the unprocessed seeds. Non- antioxidant enzymes, vitamin A, vitamin E and vitamin C content was high in both soaked and roasted flaxseed. Antioxidant activity was high in roasted and soaked flaxseed. Thus the presence of these phytonutrient and antioxidant activity of processed namely roasted and soaked flaxseeds indicates that, it has a potential of being used in formulations prepared for food consumption. Flaxseed could also be a remedy for the major killer diseases like cancer, diabetes and cardiovascular diseases.

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COMPARATIVE EVALUATION OF ANTIDAIBETIC ACTIVITIES IN PATIENTS OF TYPE II DIABETES MELLITUS TREATED WITH ACARBOSE ALONE AND IN COMBINATION WITH SALACIA SPECIES

A D Landge¹*, C R Pawar², S R Chaudhari¹, P R Gade³

¹Amrutvahini College of Pharmacy Sangamner 422605, Dist Amhednagar Maharashtra India.

² Govt. Polytechnic College Dept of Pharmacy Jalgaon 425001 Maharashtra.

³Maharashtra Institute of Medical Science and Research Latur 413512 Maharashtra.

SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF ISONIAZID AND PYRIDOXINE

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PHYTONUTRIENT COMPOSITION AND ANTIOXIDANT ACTIVITY OF PROCESSED FLAXSEED

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COMPARATIVE EVALUATION OF ANTIDAIBETIC ACTIVITIES IN PATIENTS OF TYPE II DIABETES MELLITUS TREATED WITH ACARBOSE ALONE AND IN COMBINATION WITH SALACIA SPECIES

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ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF SUNITINIB MALATE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORM USING RP-HPLC

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SPECTROPHOTOMETRIC DETERMINATION OF LEVETIRACETAM USING 2, 4-DNP IN PHARMACEUTICAL DOSAGE FORM

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DEVELOPMENT AND VALIDATION OF CHEMOMETRIC ASSISTED UV SPECTROPHOTOMETRIC AND RPLC-PDA METHODS FOR THE SIMULTANEOUS IN VITRO ANALYSIS OF ISONIAZID, RIFAMPICIN AND PIPERINE IN THEIR PHARMACEUTICAL FORMULATION

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SYNTHESIS, CHARACTERISATION AND BIOLOGICAL EVALUTION OF SOME NOVEL 6-FLUORO BENZOTHIAZOLE SUBSTITUTED THIAZOLIDINONES AS ANTI-OXIDANT AND ANTIMICROBIAL AGENTS

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PRESCRIBING PATTERNS OF ANTIBIOTICS IN POST OPERATIVE PATIENTS IN A TEACHING HOSPITAL

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A REVIEW ON HEALTH BENEFITS OF SCALAR ENERGY

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STABILITY INDICATING HPTLC METHOD FOR DETERMINATION OF EPROSARTAN MESYLATE FROM BULK DRUG AND PHARMACEUTICAL FORMULATIONS

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CNS DEPRESSANT, OPIOID TYPE OF ANALGESIC & ANTI-HISTAMINE ACTIVITIES OF BASELLA ALBA VAR RUBRA (LINN) STEWART

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HEPATOPROTECTIVE ACTIVITY OF HERBAL FORMULATION AGAINST PARACETAMOL-INDUCED HEPATOTOXICITY IN RATS

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IN-VITRO AND EX-VIVO EVALUATION OF MUCOADHESIVE TABLETS USING NATURAL POLYMERS BY GASTRO RETENTIVE DRUG DELIVERY SYSTEM

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EFFECTS OF PARTICLE SIZE AND SOME FORMULATION ADDITIVES ON THE DISSOLUTION PROFILE OF IBUPROFEN FROM COMPRESSED TABLETS.

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PREDICTION OF BINDING ENERGIES/INTERACTIONS BETWEEN DIOSPYRIN AND DIFFERENT TARGET PROTEINS OF Mycobacterium tuberculosis BY IN SILICO MOLECULAR DOCKING STUDIES

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A NEW RP-HPLC ANALYTICAL METHOD DEVELOPMENT & VALIDATION FOR ESTIMATION OF LORNOXICAM IN BULK AS WELL AS IN PHARMACEUTICAL FORMULATION BY USING PDA DETECTOR

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ANXIOLYTIC EFFECT OF MEDICAGO SATIVA SEEDS EXTRACT ON RODENTS

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PREPARATION AND EVALUATION OF NANOSUSPENSIONS FOR ENHANCING THE DISSOLUTION OF LORNOXICAM BY ANTISOLVENT PRECIPITATION TECHNIQUE

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SOLID DISPERSION STRATEGY TO ENHANCE SOLUBILITY AND DISSOLUTION RATE OF POORLY AQUEOUS SOLUBLE DRUG-AN UPDATED REVIEW

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CARDIOVASCULAR DRUG LOADING: A WURSTER BASED DRUG DELIVERY TECHNOLOGY

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A REVIEW ON: ANALYTICAL METHODOLOGY AND INSTRUMENTATION

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SYNTHESIS AND BIOLOGICAL EVALUATION OF (6-CHLORO-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID ESTERS AS ANTI-INFLAMMATORY AGENTS DEVOID OF ULCEROGENIC POTENTIAL AT THE TESTED DOSE LEVEL

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SOLID DISPERSION STRATEGY TO ENHANCE SOLUBILITY AND DISSOLUTION RATE OF POORLY AQUEOUS SOLUBLE DRUG-AN UPDATED REVIEW