IAJPR

Indo American Journal of Pharmaceutical Research

ISSN NO.: 2231-6876
MAY 2024
1

FORMULATIONANDEVALUATIONOFMULTIPURPOSEHERBAL SHAMPOO

Vivek K. Patil*, YateshR. Patil, Mayur A. Patkari, Roshan M. Chaudhari, Sunil P. Pawar

Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India.

Herbal Shampoo is a cosmetic preparation which uses herbs and it is meant for washing of hair and scalp just like a regular shampoo. Shampoos are the products which removes surface grease, dust from the hair shaft The herbal shampoo was formulated natural ingredients like Emblicaofficinalis Gaerth (Amla), Azadirachtaindica (Neem), Acacia Arabica (Shikakai), Spindusmukorossi (Reetha), Murrayakoenigii (Curryleaves), Ecliptaalba (Bhringraj), Aloe barbadensis miller (Aloe). The formulation at laboratory scale was done and evaluated for number of parameter to ensure its safety and efficacy. Three formulations was prepared i.e F1, F2 and F3 and the evaluation parameters was studied like Foam stability, pH test, Detergency and cleansing action, Physical appearance, etc. Formulation F3 was showing good pH, good detergency and cleansing action, good physical appearance as compared to other formulation. 


 


2

GLIMPSES ON VALIDATION OF ASSAY METHOD FOR ESTIMATION OF ITRACONAZOLE IN ITRACONAZOLE TABLET DOSAGE FORM BY UV-SPECTROSCOPY

Jyoti R.Gadhe*, Rashid Azeez, Vinod A. Bairagi

Department of Pharmaceutical Quality Assurance, K.B.H.S.S.Trust’s Institute of Pharmacy & Research Center, affiliated to Savitribai Phule Pune University, Bhayegaon, Malegaon, Nashik, Maharashtra, India.

A simple, precise, quick, and affordable UV spectrophotometric technique is created and proven to be effective for figuring out the dosages of itraconazole in tablets and bulk. The drug is soluble in organic solvents like methanol, ethanol, and dimethyl forma-amide. Itraconazole in tablet form can be measured simply, rapidly, and economically with the UV method. UV spectroscopic analysis are conduct at an absorption maximum of 262 nm using methanol as a solvent. In accordance with ICH criteria, the suggested approach was verified for linearity, precision, accuracy, sensitivity, and robustness. This review is really comprehensive, and the procedure for measuring itraconazole is simple and accurate method. 


 


3

A NOVEL VALIDATED ASSAY METHOD FOR QUANTIFICATION OF FLUCONAZOLE IN MARKETED FLUCONAZOLE TABLET DOSAGE FORM BY ULTRAVIOLET SPECTROSCOPY: REVIEW

Khushali Deshmukh*, Rashid Azeez, Vinod A. Bairagi

Department of Pharmaceutical Quality Assurance, K.B.H.S.S.Trust’s Institute of Pharmacy & Research Center, affiliated to Savitribai Phule Pune University, Bhayegaon, Malegaon, Nashik, Maharashtra, India.

A simple, accurate, rapid and inexpensive UV spectrophotometric method was developed and validated for the determination of fluconazole in bulk and tablet doses. The drug is soluble in organic solvents such as ethanol and dimethyl forma-amide. Using the UV method, only fluconazole in tablet form can be measured easily, quickly and cost-effectively. The absorption maximum of fluconazole is between 200 and 260 nm. The proposed method was validated for linearity, precision, accuracy, sensitivity and robustness as per ICH guidelines. This review is very informative and you can easily measure fluconazole with this simple and accurate method. 


 


4

FORMULATION AND EVALUATION OF HERBAL EMULGEL LOADED WITH EXTRACT OF BUCHANANIALANZAN LEAVES

Pooja A.Chimane*, Priyanka D. Mangale, Rubina U. Watangi

Department of Pharmacology, Sant Gajanan Maharaj College of Pharmacy, Mahagaon, Kolhapur, Maharashtra. 416503.

The present study aimed to develop and evaluate a novel herbal emulgel formulation loaded with the extract of Buchananialanzan leaves. Buchananialanzan, commonly known as Chironji, is a medicinal plant with various therapeutic properties. The emulgel formulation was prepared using a combination of hydrophilic and lipophilic ingredients to achieve optimal stability, spreadability, and drug release characteristics.The extract of Buchananialanzan leaves was obtained using a extraction method. The extract was characterized for its phytochemical composition, which revealed the presence of bioactive compounds such as flavonoids, phenolics, and alkaloids. These compounds are known for their antioxidant and anti-inflammatory activities, making them promising candidates for topical applications. The emulgel formulation was developed by incorporating the Buchananialanzan leaf extract into a gel matrix composed of a hydrophilic polymer, a lipophilic phase, and suitable emulsifiers. Various evaluation parameters including pH, viscosity, spread ability were investigated to assess the quality of the formulated emulgel. The optimized formulation exhibited desirable physical characteristics and uniform drug content. In conclusion, the formulation and evaluation of a herbal emulgel loaded with Buchananialanzan leaf extract offer a promising approach for utilizing the medicinal properties of this plant. The developed emulgel demonstrated good physical characteristics, sustained drug release, and excellent skin compatibility. Further studies are warranted to explore the therapeutic efficacy of the Buchananialanzanemulgel in the management of various skin conditions and to understand its mechanism of action. 


 


5

UNVEILING THE POWER OF PLANTS: A REVIEW ON HERBAL SUNSCREENS

Sakshi Rani, Diya Sharma, Mohammad Khalid*, Dr. Ankit Kumar, Dr. Dashrath Singh, Megha Gupta

Krishna Pharmacy College, Bijnor Uttar Pradesh, India – 246701.

Creating sunscreen cream formulations with a high sun protection factor (SPF) & desirable properties was the aim of this study. Skin conditions such as sunburn and the associated symptoms of extended exposure have been linked to ultraviolet (UV) radiation. Because of its capacity to reflect, absorb, and scatter UV light, sunscreens have shown to be helpful in lowering the prevalence of skin conditions such as sunburn, skin aging, and immune-suppression. The most common method these days for shielding our skin against them is to use sunscreen. Sunscreens are put through frequent testing and given a SPF (Sun Protection Factor) based on how well they shield skin. Due to their ability to induce leukocytosis, allergic reactions, damage DNA (deoxyribonucleic acid), reduce organ weight, and even cause anemia, the majority of synthetic sunscreen ingredients are extremely dangerous to humans.