IAJPR

Indo American Journal of Pharmaceutical Research

ISSN NO.: 2231-6876
JULY 2022
1

A REVIEW ON PHYTOPHARMACOLOGICAL ACTIVITY OF ALPINIA GALANGA

Miss. Sadhna Sing, Dr Arvind Negi

Department of Pharmacognosy (GRD) Institute of Management and Technology.

Department of Pharmacy Rajpur Road Dehradun Uttarakhand.

Alpinia galanga plant which is associated with family Zingiberaceae is mainly scattered in tropical areas and widely known for ethno medicine. Against fungi and bacteria rhizome extract have a maximum inhibitory effect. Alpinia galanga plant is used in medicine and in food preparation. Rhizome extract of Alpinia galanga have high phenolic and flavonoid contents when compared to leaf extract. Because of elevated phenolic and flavonoid content in rhizome extract of Alpinia galanga there is noticeable antimicrobial as well as radical scavenging potential. It is a well-known official drug thought out the country as integrated contribution of nature. It is commonly used for the management of eczema, coryza, bronchitis, otitis interna, gastritis, ulcers, morbilli and cholera, pityriasis versicolor, to clear the mouth, emaciation. The different parts of the plant have various effects like antifungal, antiprotozoal, antiplatelet, antiviral, antidiabetic, immunomodulatory, antibacterial, anti-oxidant effects, hypolipidemic and many others. The essential oil of A. galanga identified 1, 8-cineol as a bioactive agent having antifeeding activity. An aqueous acetone extract of fruit of Alpinia galanga shows inhibitory effect on melanogenesis (formation of melanin). By using different methods, active constituent namely, 1'- acetochavicol acetate in hexane extract of Alpinia galanga rhizome was investigated for their corrosion inhibition properties. The current review add significant information about its, pharmacological activities, medicinal properties and phytochemical investigations as a traditional drug to cure for a number of diseases. Every fraction of the plant has valuable properties that can deliver humanity. The complete plant will be broadly investigated for further future prospective. 


 


2

IDENTIFICATION OF DRUG RELATED PROBLEMS IN PATIENTS VISITING GENERAL WARD IN TERTIARY CARE HOSPITAL: A PROSPECTIVE, OBSERVATIONAL STUDY

Hardi Patel, Dhvani Patel, Ruchi Yadav,Yesha Joshi, Dr. KalpeshChopda

¹Shree Dhanvantary Pharmacy College, Kim, Surat, Gujarat – 394111.

2Department of General Medicine, Kiran Multi Super Specialty Hospital and Research Center, Surat, Gujarat – 395004.

Background: The Drug Related Problems (DRPs) are the unwanted and undesirable effects caused within any phase of Pharmaceutical care which can actually or potentially interfere with desired health outcome and may cause drug-related morbidity and mortality. Objective: This study aims at assessment of the DRPs in patients admitted to the General Ward of tertiary care hospital in India by using Pharmaceutical Care Network Europe Classification. Materials and Methods: A prospective, observational study was conducted for 200 patients at the general ward of tertiary care hospital in Surat between December 2020 to March 2021. DRPs were assessed and categorized via Pharmaceutical Care Network Europe Classification. Results: Medication charts of 200 patients were analyzed. The patients’ median age was 51.3 years and 57% of patients were prescribed with polypharmacy. The average length of stay per patient was 4.8 days. 74% patients had at least one comorbid condition among which hypertension and diabetes mellitus were most common. In 84% of patients, the major reason for admission was cardiovascular diseases. A total number of 2246 medication orders were reviewed and majorly prescribed agents were gastrointestinal agents(20.3%), cardiovascular agents(15.9%) and antimicrobial agents(15.6%). In 16 patients, 21 clinical actual DRPs were detected. The most frequent clinical DRPs were treatment effectiveness (33.7%). Antimicrobial agents(29%) and cardiovascular agents(22%) drug classes were responsible for the majority of DRPs. Prevalent causes of DRPs were found to be selection of drugs(42.8%), dose selection(23.7%) and patient related(4.7%). Conclusion: The DRPs cannot be ceased immediately but can be prevented by active and rationalized pharmaceutical care. The problem arising from pharmacotherapy can be identified, resolved by the upgraded clinical knowledge and patient centric pharmacotherapeutic management. 


 


3

FORMULATION AND EVALUATION OF HERBAL FACE PACK

Momin Rehan K.1*, Shejal Supriya B.1, Irkar Kiran S.1, Hajare Utkarsha S.1, Minchikar Sarvesh K.1, Satpute Savita S.2

1Adarsh College of Pharmacy, Vita (MS) India.

2Department of Pharmaceutical Chemistry, Adarsh College of Pharmacy, Vita (MS) India.

The demand for herbal cosmetics is rising on the international market. The purpose of the current effort is to prepare and evaluate a herbal face pack for skin utilising a variety of natural powders. Shade-dried commercial date powder, bael fruit powder, sandalwood powder, liquorice powder, honey powder, and lemon powder are among the natural powders utilised. All of the powdered natural ingredients were purchased from a local market in the form of dried powder. They were then accurately weighed, mixed geometrically for uniform preparation, and evaluated for parameters such as organoleptic, physical, Physicochemical, phytochemical constituents, irritancy, as well as stability studies. As a result, we developed a herbal face pack in this study using components that were easily available. After evaluation, we found good flow characteristics, no skin irritants and stable storage conditions. Result of this study provided scientific confirmation that herbal face packs have the capacity to effectively reduce skin ageing. These compositions produce positive results and promote skin health without having any negative side effects.The demand for herbal cosmetics is rising on the international market. The purpose of the current effort is to prepare and evaluate a herbal face pack for skin utilising a variety of natural powders. Shade-dried commercial date powder, bael fruit powder, sandalwood powder, liquorice powder, honey powder, and lemon powder are among the natural powders utilised. All of the powdered natural ingredients were purchased from a local market in the form of dried powder. They were then accurately weighed, mixed geometrically for uniform preparation, and evaluated for parameters such as organoleptic, physical, Physicochemical, phytochemical constituents, irritancy, as well as stability studies. As a result, we developed a herbal face pack in this study using components that were easily available. After evaluation, we found good flow characteristics, no skin irritants and stable storage conditions. Result of this study provided scientific confirmation that herbal face packs have the capacity to effectively reduce skin ageing. These compositions produce positive results and promote skin health without having any negative side effects.